DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment en2b and Ptx1

DIOPT Version :9

Sequence 1:	NP_571115.1	Gene:	en2b / 30238	ZFINID:	ZDB-GENE-980526-40	Length:	261	Species:	Danio rerio
Sequence 2:	NP_001138130.2	Gene:	Ptx1 / 43664	FlyBaseID:	FBgn0020912	Length:	610	Species:	Drosophila melanogaster

Alignment Length:	90	Identity:	34/90 - (37%)
Similarity:	51/90 - (56%)	Gaps:	5/90 - (5%)

- Green bases have known domain annotations that are detailed below.

Zfish   152 DRP--SSGPRSRKPKKKTPTKEDKRPRTAFTAEQLQRLKNEFQNNRYLTEQRRQALAQELGLNES 214
            |.|  :||   .:||.....|..:|.||.||::|||.|::.|..|||.....|:.:|....|.|:
  Fly   245 DEPMTTSG---EEPKNDKKNKRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEA 306

Zfish   215 QIKIWFQNKRAKIKKATGNKNTLAV 239
            ::::||:|:|||.:|...|....||
  Fly   307 RVRVWFKNRRAKWRKRERNAMNAAV 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
en2b	NP_571115.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	53..125
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	152..176		8/25 (32%)
		Homeobox	175..228	CDD:278475	22/52 (42%)
		Engrail_1_C_sig	230..259	CDD:287495	3/10 (30%)
Ptx1	NP_001138130.2	Homeobox	268..320	CDD:278475	22/51 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000