DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tnn and CG9500

DIOPT Version :9

Sequence 1:	XP_005171321.1	Gene:	tnn / 30234	ZFINID:	ZDB-GENE-990415-262	Length:	1020	Species:	Danio rerio
Sequence 2:	NP_609018.3	Gene:	CG9500 / 33888	FlyBaseID:	FBgn0031804	Length:	292	Species:	Drosophila melanogaster

Alignment Length:	267	Identity:	84/267 - (31%)
Similarity:	132/267 - (49%)	Gaps:	21/267 - (7%)

- Green bases have known domain annotations that are detailed below.

Zfish   747 TARENRFALSGLEMGKKYIVTLIAYRGSKRS----KIVETTFSTVGLAYQFPMDCTQIMRNGNME 807
            ||..|:..|..|   .|.::.|:....|..|    :...:..:|.||:.::|..|...    ...
  Fly    30 TAIRNKPELKSL---YKLVLALLEENQSNASTENIQKSSSDLNTTGLSGRYPSQCPTY----PPA 87

Zfish   808 SGVYTIYVNNNRSRTMQVYCDMKTDGGGWIVFQRRNTGKVDFMKKWRDYMKGFGELTEEFWLGLD 872
            .|:||:.|..  .:..||.||.:..|.||.|..||.:.|::|.:.|.:|..|||:|..:|::|||
  Fly    88 HGIYTVQVLG--LKPFQVSCDAEIAGTGWTVMARRTSNKLNFFRSWAEYKNGFGQLDGDFFIGLD 150

Zfish   873 KIHELTNT-PTQYEARFDLGSGSDRKYAVYDNFKVAPSKQKFKLT-IGSYKGNAGDAMTYHQGAP 935
            |:|.:|.: |.:.....:...|..| ||.||...:....:.:.:| :|.:.|:|||:|.:::...
  Fly   151 KLHAITKSQPHELYIHLEDFEGQTR-YAHYDEIFIESENKFYAMTKLGEFTGDAGDSMIHNRNQN 214

Zfish   936 FSTVDSDNDIALGNCALTHQGAWWYKNCHLANLNGRF--GDNRHSM---GVNWEPWKGHLQSLDF 995
            |||.|.|||....|||..:.||||:.||..:||.|.:  ||.....   |:.|..|:....|...
  Fly   215 FSTFDRDNDGWHKNCAEEYVGAWWHLNCTYSNLFGIYVKGDEGQYFQWKGIVWHSWRTESYSYKV 279

Zfish   996 AEIKIRP 1002
            .::.:||
  Fly   280 MQMMVRP 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tnn	XP_005171321.1	EGF_alliinase	<133..163	CDD:282688
		EGF_2	161..189	CDD:285248
		EGF_2	193..220	CDD:285248
		EGF_2	224..251	CDD:285248
		fn3	257..333	CDD:278470
		fn3	344..426	CDD:278470
		fn3	435..514	CDD:278470
		fn3	523..602	CDD:278470
		fn3	611..683	CDD:278470
		fn3	699..773	CDD:278470	7/25 (28%)
		FReD	792..1003	CDD:238040	72/218 (33%)
CG9500	NP_609018.3	FReD	76..287	CDD:238040	72/218 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100073
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.710