DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment inab and LamC

DIOPT Version :9

Sequence 1:	NP_571107.2	Gene:	inab / 30230	ZFINID:	ZDB-GENE-990415-83	Length:	469	Species:	Danio rerio
Sequence 2:	NP_001260974.1	Gene:	LamC / 36615	FlyBaseID:	FBgn0010397	Length:	640	Species:	Drosophila melanogaster

Alignment Length:	489	Identity:	135/489 - (27%)
Similarity:	221/489 - (45%)	Gaps:	105/489 - (21%)

- Green bases have known domain annotations that are detailed below.

Zfish    10 ASSYRKIFGDSTRFSASPSRLSSSRSGFKSQSVNRPNIPSSYKRSTRSGFPSSSLDSFDFTQSTV 74
            ||:...:.|.||          |||.|..|        |:|..|::|.
  Fly    15 ASTSTPVGGAST----------SSRVGATS--------PTSPTRTSRQ----------------- 44

Zfish    75 LNNEFKIIRTNEKEQMQGLNDRFAMFIEKVRNLEQHNKVLETELVTLRQR--QTEPSRLAELYQQ 137
                      .|||::|.||||.|.:|:::||||..|..|..|| .|.|.  ..|.|.|..:|::
  Fly    45 ----------QEKEELQHLNDRLACYIDRMRNLENENSRLTQEL-NLAQDTVNRETSNLKAVYEK 98

Zfish   138 EIRELRSQLEELNAEK-------NQMMFERDSIEEDLQK-------------LHE---------- 172
            |:...|..|:|...||       .::..|.|.::..|.|             |:|
  Fly    99 ELAAARKLLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKY 163

Zfish   173 --------KFEEEMR----MREEAEQTLRAFKKDVDNASMVRLDLEKKVESLLDEINFLRKVHEE 225
                    |||::.:    ..|...:.|...:|.::..::.|:|||.:.:||.:|:.|..:||.:
  Fly   164 NQSLADRKKFEDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQ 228

Zfish   226 EVAELMNMIQASQVSVEMEVAK---PDLTSALKDIRGQYEAMASKNLQSAEEWYKSKFADLSEQA 287
            |:.|..:..|.....::..:::   ..|..:|:::|.|||.....|.:..|..|.::..:|...|
  Fly   229 ELTETRSRRQIEISEIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAA 293

Zfish   288 NKSNEVIRASREELNEFRRQLQSKTIEIESLRGTNESLERQIHEMEDRHNAEIMGYQDSIGELEN 352
            |::.:....:.||:...|.::.....::::|..||..|..:|.|:|:..:.|...:...|..||.
  Fly   294 NRAAQGSALATEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEA 358

Zfish   353 DLRTTKSEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRISTGITYP----TPASVSSYSY 413
            :|:..:.|||..|:|||.|:::|::||:|||||.|||.|||.|::  |..|    |.:.:||..
  Fly   359 ELQRMRDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRLN--IESPGRPTTDSGISSNG- 420

Zfish   414 QSRLYSSTSMSSKKEVKDDDDKQQSGKPG-KGSS 446
             |.|.:|.|..|.:.....   ::|..|| .|||
  Fly   421 -SHLTASASSRSGRVTPSG---RRSATPGISGSS 450

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inab	NP_571107.2	Filament_head	8..84	CDD:282575	14/73 (19%)
inab	NP_571107.2	Filament	85..395	CDD:278467	104/356 (29%)
LamC	NP_001260974.1	Filament	45..401	CDD:278467	104/356 (29%)
		ATP-synt_B	<67..>142	CDD:304375	22/75 (29%)
		MreC	<178..>224	CDD:302802	11/45 (24%)
		LTD	473..574	CDD:279300
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910