DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2BC5 and His2B:CG33868

DIOPT Version :9

Sequence 1:	XP_005249096.1	Gene:	H2BC5 / 3017	HGNCID:	4747	Length:	150	Species:	Homo sapiens
Sequence 2:	NP_001027385.1	Gene:	His2B:CG33868 / 3772265	FlyBaseID:	FBgn0053868	Length:	123	Species:	Drosophila melanogaster

Alignment Length:	129	Identity:	103/129 - (79%)
Similarity:	107/129 - (82%)	Gaps:	9/129 - (6%)

- Green bases have known domain annotations that are detailed below.

Human    25 MPEPTKSAPAPKKGSKKAVTKAQK---KDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGI 86
            ||..|....|.|.|      ||||   |..||:||.|||||::|:||||||||||||||||||.|
  Fly     1 MPPKTSGKAAKKAG------KAQKNITKTDKKKKRKRKESYAIYIYKVLKQVHPDTGISSKAMSI 59

Human    87 MNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK 150
            |||||||||||||.||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly    60 MNSFVNDIFERIAAEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK 123

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2BC5	XP_005249096.1	Histone	20..126	CDD:278551	77/103 (75%)
H2BC5	XP_005249096.1	H2B	36..149	CDD:304987	96/115 (83%)
His2B:CG33868	NP_001027385.1	H2B	33..121	CDD:197718	82/87 (94%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1744
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100082
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.800