DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment neurod1 and Fer3

DIOPT Version :9

Sequence 1:	NP_571053.1	Gene:	neurod1 / 30169	ZFINID:	ZDB-GENE-990415-172	Length:	350	Species:	Danio rerio
Sequence 2:	NP_524322.1	Gene:	Fer3 / 41411	FlyBaseID:	FBgn0037937	Length:	195	Species:	Drosophila melanogaster

Alignment Length:	155	Identity:	49/155 - (31%)
Similarity:	71/155 - (45%)	Gaps:	36/155 - (23%)

- Green bases have known domain annotations that are detailed below.

Zfish    75 KPKRRG-----PKKKKMTKARMQRFKMRRMKANARERNRMHGLNDALESLRKVVPCYSKTQKLSK 134
            :|...|     ....|.|:.|:.....|| .||.|||.||..||:|.:.||:.||.::..::||:
  Fly    61 RPSTNGRANGSSSSSKKTRRRVASMAQRR-AANIRERRRMFNLNEAFDKLRRKVPTFAYEKRLSR 124

Zfish   135 IETLRLAKNYIWALSEILRSGKSPDLMSFVQALCKGLSQPTTNLVAGCLQLNPRTFLPEQSQEMP 199
            |||||||..||..::|:| ||...:            |..:.:.|.|.:.        ...|..|
  Fly   125 IETLRLAITYIGFMAELL-SGTPSN------------SHKSRSDVYGSMN--------GHHQAPP 168

Zfish   200 P-----HMQTASA---SFSALPYSY 216
            |     |:..|:|   .| |.||::
  Fly   169 PAIHPHHLHPAAAYQRDF-ASPYNH 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neurod1	NP_571053.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..91		4/20 (20%)
		Nuclear localization signal. /evidence=ECO:0000255	82..88		1/5 (20%)
		HLH	95..153	CDD:238036	28/57 (49%)
		Neuro_bHLH	155..277	CDD:289310	14/70 (20%)
Fer3	NP_524322.1	HLH	87..135	CDD:278439	25/48 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910