Protein Alignment lft2 and scw

DIOPT Version :9

• Sequence 1: NP_571036.1
• Gene: lft2 / 30146
• ZFINID: ZDB-GENE-990630-11
• Length: 362
• Species: Danio rerio
• Sequence 2: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Alignment Length: 445
• Identity: 91/445 - (20%)
• Similarity: 164/445 - (36%)
• Gaps: 142/445 - (31%)

Zfish     5 IQLFILTT----AISLTQGFQHEDIKQALLQKLGLTE-------------PPRIQKRDLENLVVP 52
            :.:|.||:    |.:.|....:..|:..:.||..|:|             |.|..:.:|.|..
  Fly     2 LNVFFLTSLFYAASATTYVTTNNHIEMPIYQKRPLSEQMEMIDILDLGDRPRRQAEPNLHNSA-- 64

Zfish    53 AHIKSKYLSMLKLH-------------HQRRRRSLPSLAGILRGIHGNADITGEIKYSDTTRQRL 104
                ||:|  |:::             |||.:|||..                :|..|:..||.:
  Fly    65 ----SKFL--LEVYNEISEDQEPKEVLHQRHKRSLDD----------------DILISNEDRQEI 107

Zfish   105 -----VFDMEARLQE-------------NTEVTMAELKLFQTAA---QSPSKPERRHHRPINHAR 148
                 :....:||:.             ||.....:|.|.|...   :.||..:||     .:..
  Fly   108 ASCNSILTFSSRLKPEQLDNELDMHITFNTNDVPVDLSLVQAMLRIYKQPSLVDRR-----ANFT 167

Zfish   149 VSIYWVEVLENGSNRT-SLLDSRLVPIHESGWRSFDVTQAIHYWSKS---QKKAPLHLEVWTEGE 209
            ||:|  ..|:|..:.: .:|.|......:.||..|::|..:.||..:   |::..|.:.:   |:
  Fly   168 VSVY--RKLDNRQDFSYRILGSVNTTSSQRGWLEFNLTDTLRYWLHNKGLQRRNELRISI---GD 227

Zfish   210 -RPGSYAAEMAKRVRFATQDPKENTLEKDM----GAPELVL------YTLDLDEYGSQGNCNSSP 263
             :..::||.:      .|......:||..:    ..|||::      :..||::..:.|.....|
  Fly   228 SQLSTFAAGL------VTPQASRTSLEPFIVGYFNGPELLVKIQKLRFKRDLEKRRAGGGSPPPP 286

Zfish   264 --------NSSKCCREEHF-INFRELTWTQYWIIEPAGYQAFRCAGGCKQPKRGFYGYGQRTCAV 319
                    ...:.|...:| ::|:|| ....|:|.|..::|:.|.|||..|      .|.:..|.
  Fly   287 PPPPVDLYRPPQSCERLNFTVDFKEL-HMHNWVIAPKKFEAYFCGGGCNFP------LGTKMNAT 344

Zfish   320 MESAPLPMMYLVKK------------GDYT--------EIEVAEFPNMIVEKCGC 354
            ..:....:|:|.:.            |..|        .|::.::...:.::|||
  Fly   345 NHAIVQTLMHLKQPHLPKPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGC 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lft2	NP_571036.1	TGFb_propeptide	15..204	CDD:366248	50/239 (21%)
		TGF_beta_LEFTY1_2	267..354	CDD:381636	22/107 (21%)
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	50/254 (20%)
		TGFB	300..400	CDD:214556	24/107 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810