DRSC/TRiP Functional Genomics Resources

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Protein Alignment H2AX and His2A:CG33832

DIOPT Version :10

Sequence 1:NP_002096.1 Gene:H2AX / 3014 HGNCID:4739 Length:143 Species:Homo sapiens
Sequence 2:NP_001027331.1 Gene:His2A:CG33832 / 3772632 FlyBaseID:FBgn0053832 Length:124 Species:Drosophila melanogaster


Alignment Length:121 Identity:110/121 - (90%)
Similarity:116/121 - (95%) Gaps:1/121 - (0%)


- Green bases have known domain annotations that are detailed below.


Human     1 MSGRGKTGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGHYAERVGAGAPVYLAAVLEYLTAEILE 65
            |||||| |||.:.||||||:||||||||||:|||||||:||||||||||||||||:|||.||:||
  Fly     1 MSGRGK-GGKVKGKAKSRSNRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLE 64

Human    66 LAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKT 121
            |||||||||||||||||||||||||||||||||.||||||||||||||||||||||
  Fly    65 LAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKT 120

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
H2AXNP_002096.1 PTZ00017 1..131 CDD:185399 110/121 (91%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..22 15/20 (75%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 121..143 1/1 (100%)
[ST]-Q motif 140..141
His2A:CG33832NP_001027331.1 PTZ00017 16..124 CDD:185399 98/105 (93%)
Blue background indicates that the domain is not in the aligned region.

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