DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment frzb and smo

DIOPT Version :9

Sequence 1:	NP_571018.1	Gene:	frzb / 30119	ZFINID:	ZDB-GENE-990715-1	Length:	315	Species:	Danio rerio
Sequence 2:	NP_523443.1	Gene:	smo / 33196	FlyBaseID:	FBgn0003444	Length:	1036	Species:	Drosophila melanogaster

Alignment Length:	184	Identity:	41/184 - (22%)
Similarity:	67/184 - (36%)	Gaps:	31/184 - (16%)

- Green bases have known domain annotations that are detailed below.

Zfish    12 CVLAFACLLEIPRGTGAASCEPIRIPMCKSMPWNMTKMPNHLHHSTQANAVLAIEQFEGLLGTQC 76
            ||....|   .|......:|...::|. :....::|........:.:.|...|::..     .:|
  Fly    84 CVRRARC---YPTSNATNTCFGSKLPY-ELSSLDLTDFHTEKELNDKLNDYYALKHV-----PKC 139

Zfish    77 SADLLFFLCAMYAPIC-TIDFQHDPIKPCKSVCERAKCGCEPVMKRYNHT-WPESLACEE----- 134
            .|.:..||||::.|.| .|:.:.....|...:|   :...||....||.| :|:.|.|.|
  Fly   140 WAAIQPFLCAVFKPKCEKINGEDMVYLPSYEMC---RITMEPCRILYNTTFFPKFLRCNETLFPT 201

Zfish   135 --------LPVYDRGVCISPEAIVKAEGPDNSYYQDPAKCNPE-GNPDFPMDSH 179
                    :.....|.|:||  :|..: ...|||.....|... .:|.:..|.|
  Fly   202 KCTNGARGMKFNGTGQCLSP--LVPTD-TSASYYPGIEGCGVRCKDPLYTDDEH 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
frzb	NP_571018.1	CRD_SFRP3	28..153	CDD:143550	30/139 (22%)
frzb	NP_571018.1	NTR_Sfrp3_like	200..310	CDD:239636
smo	NP_523443.1	CRD_SMO	86..221	CDD:143560	29/146 (20%)
smo	NP_523443.1	Frizzled	246..568	CDD:279827	2/7 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810