DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cat and Cat

DIOPT Version :9

Sequence 1:	NP_570987.2	Gene:	cat / 30068	ZFINID:	ZDB-GENE-000210-20	Length:	526	Species:	Danio rerio
Sequence 2:	NP_536731.1	Gene:	Cat / 40048	FlyBaseID:	FBgn0000261	Length:	506	Species:	Drosophila melanogaster

Alignment Length:	489	Identity:	327/489 - (66%)
Similarity:	398/489 - (81%)	Gaps:	4/489 - (0%)

- Green bases have known domain annotations that are detailed below.

Zfish     5 REKSTDQMKLWKEGRGSQRPDVLTTGAGVPIGDKLNAMTAGPRGPLLVQDVVFTDEMAHFDRERI 69
            |:.:::|:..:|..: :..|..:|||.|.|||.|..:.|.|||||:|:|||.|.|||:|||||||
  Fly     4 RDAASNQLIDYKNSQ-TVSPGAITTGNGAPIGIKDASQTVGPRGPILLQDVNFLDEMSHFDRERI 67

Zfish    70 PERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKTTPIAVRFSTVAGEAGSSDTVRDPRGFAV 134
            |||||||||||||||||||||||:|..||:|:.:.|.||:|||||||.||:||:||.||||||||
  Fly    68 PERVVHAKGAGAFGYFEVTHDITQYCAAKIFDKVKKRTPLAVRFSTVGGESGSADTARDPRGFAV 132

Zfish   135 KFYTDEGNWDLTGNNTPIFFIRDTLLFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFL 199
            ||||::|.|||.|||||:|||||.:|||||||:||||||||||||||.|||.:|||||.|||..|
  Fly   133 KFYTEDGVWDLVGNNTPVFFIRDPILFPSFIHTQKRNPQTHLKDPDMFWDFLTLRPESAHQVCIL 197

Zfish   200 FSDRGIPDGYRHMNGYGSHTFKLVNAQGQPVYCKFHYKTNQGIKNIPVEEADRLAATDPDYSIRD 264
            |||||.||||.||||||||||||:||:|:|:|.|||:||:|||||:.|:.||:||:|||||||||
  Fly   198 FSDRGTPDGYCHMNGYGSHTFKLINAKGEPIYAKFHFKTDQGIKNLDVKTADQLASTDPDYSIRD 262

Zfish   265 LYNAIANGNFPSWTFYIQVMTFEQAENWKWNPFDLTKVWSHKEFPLIPVGRFVLNRNPVNYFAEV 329
            |||.|....|||||.||||||:|||:.:|:||||:|||||.||:||||||:.||:|||.||||||
  Fly   263 LYNRIKTCKFPSWTMYIQVMTYEQAKKFKYNPFDVTKVWSQKEYPLIPVGKMVLDRNPKNYFAEV 327

Zfish   330 EQLAFDPSNMPPGIEPSPDKMLQGRLFSYPDTHRHRLGANYLQLPVNCPYRTRVANYQRDGPMCM 394
            ||:||.|:::.||:||||||||.||||||.||||||||.||||:||||||:.::.|:||||.|.:
  Fly   328 EQIAFSPAHLVPGVEPSPDKMLHGRLFSYSDTHRHRLGPNYLQIPVNCPYKVKIENFQRDGAMNV 392

Zfish   395 HDNQGGAPNYYPNSFSAPDVQP--RFLESKCKVSPDVARYNSAD-DDNVTQVRTFFTQVLNEAER 456
            .|||.|||||:||||:.|...|  |.|.|.|.|:.||.||:|.| :||..||..|:..||::..:
  Fly   393 TDNQDGAPNYFPNSFNGPQECPRARALSSCCPVTGDVYRYSSGDTEDNFGQVTDFWVHVLDKCAK 457

Zfish   457 ERLCQNMAGHLKGAQLFIQKRMVQNLMAVHSDYG 490
            :||.||:||||..|..|:|:|.|:|...||:|:|
  Fly   458 KRLVQNIAGHLSNASQFLQERAVKNFTQVHADFG 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cat	NP_570987.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..29		4/23 (17%)
cat	NP_570987.2	catalase_clade_3	68..497	CDD:163712	296/426 (69%)
Cat	NP_536731.1	KatE	10..505	CDD:223824	326/483 (67%)
Cat	NP_536731.1	catalase_clade_3	66..498	CDD:163712	296/426 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596767
Domainoid	1	1.000	622	1.000	Domainoid score	I173
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55514
Inparanoid	1	1.050	692	1.000	Inparanoid score	I668
OMA	1	1.010	-	-		QHG62736
OrthoDB	1	1.010	-	-		D172396at33208
OrthoFinder	1	1.000	-	-		FOG0001359
OrthoInspector	1	1.000	-	-		otm25018
orthoMCL	1	0.900	-	-		OOG6_100495
Panther	1	1.100	-	-	LDO	PTHR11465
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X851
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.910