Protein Alignment RAX and toy

DIOPT Version :10

• Sequence 1: NP_038463.2
• Gene: RAX / 30062
• HGNCID: 18662
• Length: 346
• Species: Homo sapiens
• Sequence 2: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 221
• Identity: 69/221 - (31%)
• Similarity: 99/221 - (44%)
• Gaps: 56/221 - (25%)

Human   133 KKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEKL 197
            |:|.:||||:|:..|:..||:.||::|||||::||.||.|:.|||.|:||||.||||||||:||:
  Fly   262 KRKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPEARIQVWFSNRRAKWRREEKM 326

Human   198 EVS-------------------SMKLQDSPLLSFSRSPPSATLSPLGAGPGSGGGPAGGALPLES 243
            ...                   |.....|.:.:.:.|.|....|.:.....:.......:|| |:
  Fly   327 RTQRRSADTVDGSGRTSTANNPSGTTASSSVATSNNSTPGIVNSAINVAERTSSALVSNSLP-EA 390

Human   244 WLGPPLPGGGATALQSLPGFGPPAQSLPASYTPPPPPPPFLNSPPLGPGLQPLAPPPPSYPCGPG 308
            ..||.:.||.|.                .::|....||           |||.|   |..|...|
  Fly   391 SNGPTVLGGEAN----------------TTHTSSESPP-----------LQPAA---PRLPLNSG 425

Human   309 FGDKF-----PL-DEADPRNSSIAAL 328
            |...:     |: ..|:..|||:.::
  Fly   426 FNTMYSSIPQPIATMAENYNSSLGSM 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAX	NP_038463.2	Octapeptide motif	33..40
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	46..145		7/11 (64%)
		Homeodomain	137..193	CDD:459649	34/55 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..318		27/148 (18%)
		OAR	319..335	CDD:461067	3/10 (30%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	323..336		2/6 (33%)
		Nuclear localization signal. /evidence=ECO:0000255	329..333		69/221 (31%)
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863	44/105 (42%)
		Homeodomain	267..322	CDD:459649	34/54 (63%)