Protein Alignment RAX and prd

DIOPT Version :10

• Sequence 1: NP_038463.2
• Gene: RAX / 30062
• HGNCID: 18662
• Length: 346
• Species: Homo sapiens
• Sequence 2: NP_723721.1
• Gene: prd / 34629
• FlyBaseID: FBgn0003145
• Length: 613
• Species: Drosophila melanogaster
• Alignment Length: 260
• Identity: 85/260 - (32%)
• Similarity: 103/260 - (39%)
• Gaps: 82/260 - (31%)

Human   102 CPKEPGEARPSPGLPVGPATGEAKLSEEEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSR 166
            |..|||.|.                      |:|.||.||||:..||.|||||||::.|||:|:|
  Fly   201 CESEPGIAL----------------------KRKQRRCRTTFSASQLDELERAFERTQYPDIYTR 243

Human   167 EELAGKVNLPEVRVQVWFQNRRAKWRRQEKLEVS-----------SMKLQDSPLLSFSRSPPSAT 220
            ||||.:.||.|.|:||||.||||:.|:|. ..||           |.....|.|.|...|.||
  Fly   244 EELAQRTNLTEARIQVWFSNRRARLRKQH-TSVSGGAPGGAAASVSHVAASSSLPSVVSSVPS-- 305

Human   221 LSPLGAGPGSGGGPAGGALPLESWLGPPLPGGGATALQ------------SLPGFGPPAQS--LP 271
            ::||...|||              |.|      ||..|            |:....|.|.|  .|
  Fly   306 MAPLAMMPGS--------------LDP------ATVYQQQYDFYGSHANISVSAAAPMASSNLSP 350

Human   272 ASYTPPPPPPPFLN-----SPPLGPGLQPLAPPP-----PSY--PCGPGFGDKFPLDEADPRNSS 324
            ...|.||....|.|     :..:.||......|.     .||  ..|..:|.:....:..|||.|
  Fly   351 GITTTPPHHHQFYNPSANTASYIMPGENGNTTPTGNIIVSSYETQLGSVYGTETETHQTMPRNES 415

Human   325  324
              Fly   416  415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAX	NP_038463.2	Octapeptide motif	33..40
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	46..145		13/42 (31%)
		Homeodomain	137..193	CDD:459649	36/55 (65%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..318		37/160 (23%)
		OAR	319..335	CDD:461067	4/6 (67%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	323..336		1/2 (50%)
		Nuclear localization signal. /evidence=ECO:0000255	329..333
prd	NP_723721.1	PAX	27..154	CDD:238076
		Homeodomain	214..270	CDD:459649	36/55 (65%)