Protein Alignment RAX and CG32532

DIOPT Version :10

• Sequence 1: NP_038463.2
• Gene: RAX / 30062
• HGNCID: 18662
• Length: 346
• Species: Homo sapiens
• Sequence 2: NP_608318.5
• Gene: CG32532 / 32943
• FlyBaseID: FBgn0052532
• Length: 688
• Species: Drosophila melanogaster
• Alignment Length: 361
• Identity: 99/361 - (27%)
• Similarity: 139/361 - (38%)
• Gaps: 114/361 - (31%)

Human    26 GGS-TSRLHSIEAILGFTKDDGILGTFPAERGARGAKERDRRLGARPACPKAPEEGSE-----PS 84
            ||| .:||.|:.:.:..|:..  :.|.  |:.:..:....|:      |...||:.|.     |:
  Fly   379 GGSHENRLLSLASSVQDTRSP--ITTL--EKSSSSSLNHQRK------CSSTPEDFSALYSGLPT 433

Human    85 P--------------PPAPAPAPEYEAPRPYCPKEPGEARPSPGLP------VGPATGEAKLSEE 129
            |              ||:........|...:...:|   .|:.||.      ..|.:|.:.||:.
  Fly   434 PGMDSSSHHHTPAHTPPSRLSDHTISAEGAFKKLKP---EPNSGLSTVSAGITSPGSGLSSLSQH 495

Human   130 --------EQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQN 186
                    ..|....||:|||||..||.|||.||.||||||:|.|||||....|.|.|:||||||
  Fly   496 AGHTPTTASCPTPARRRHRTTFTQEQLAELEAAFAKSHYPDIYCREELARTTKLNEARIQVWFQN 560

Human   187 RRAKWRRQEKLEVSSMKLQDSPLLSFSRSPPSATLSPLGAGPGSGGGPAGGALPLESWLGPPLPG 251
            ||||:|:|||      :||.:             |:| ...|...|
  Fly   561 RRAKYRKQEK------QLQKA-------------LAP-SVIPSCNG------------------- 586

Human   252 GGATALQSLPGFGPPAQSLPASYTPPP--------PPPPFLNSPPLGPGL-QPLAPPPPSYPCGP 307
                .::::.|:     |:...|.|.|        |...|.......||: ||.:....:.....
  Fly   587 ----MMRNIQGY-----SVSRGYQPYPHHNTMNRYPQDLFQMGASSYPGMTQPFSMAHSTNMGSV 642

Human   308 G--------FGDKFPLDEADPRNSSIAALRLKAKEH 335
            |        |....|.||.  .|.|::|||:.:..|
  Fly   643 GVRQDSMGEFHGMSPEDEW--YNKSLSALRMNSSHH 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAX	NP_038463.2	Octapeptide motif	33..40		1/6 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	46..145		27/131 (21%)
		Homeodomain	137..193	CDD:459649	39/55 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..318		24/140 (17%)
		OAR	319..335	CDD:461067	5/15 (33%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	323..336		5/13 (38%)
		Nuclear localization signal. /evidence=ECO:0000255	329..333		1/3 (33%)
CG32532	NP_608318.5	Homeodomain	511..567	CDD:459649	39/55 (71%)