Protein Alignment RAX and CG11294

DIOPT Version :10

• Sequence 1: NP_038463.2
• Gene: RAX / 30062
• HGNCID: 18662
• Length: 346
• Species: Homo sapiens
• Sequence 2: NP_572500.1
• Gene: CG11294 / 31807
• FlyBaseID: FBgn0030058
• Length: 261
• Species: Drosophila melanogaster
• Alignment Length: 153
• Identity: 66/153 - (43%)
• Similarity: 87/153 - (56%)
• Gaps: 32/153 - (20%)

Human   117 VGPATGEAKLSEEEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQ 181
            :.|..|:. |:|....:::.||||||||..||.|||..|:|:|||||:.|||:|.:::|.|.|||
  Fly     6 ISPLPGDL-LTEYMFGRRRQRRNRTTFTPQQLQELEALFQKTHYPDVFLREEVALRISLSEARVQ 69

Human   182 VWFQNRRAKWRRQEKLEVSSMKLQDSPLLSFSRSPPSATLSPLGAGPGSGGGPAGGALPLESWLG 246
            |||||||||||:|.:|::    |||:..:        ..|| ||..|..|||...|.
  Fly    70 VWFQNRRAKWRKQARLQL----LQDAWRM--------RCLS-LGTPPVMGGGAVQGG-------- 113

Human   247 PPLPGGGATALQSLPGFGPPAQS 269
               .|.||||       .||:|:
  Fly   114 ---SGNGATA-------RPPSQT 126

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAX	NP_038463.2	Octapeptide motif	33..40
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	46..145		11/27 (41%)
		Homeodomain	137..193	CDD:459649	39/55 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..318		22/76 (29%)
		OAR	319..335	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	323..336
		Nuclear localization signal. /evidence=ECO:0000255	329..333
CG11294	NP_572500.1	Homeodomain	29..81	CDD:459649	35/51 (69%)