DRSC/TRiP Functional Genomics Resources

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Protein Alignment Opn4 and Rh5

DIOPT Version :10

Sequence 1:NP_038915.1 Gene:Opn4 / 30044 MGIID:1353425 Length:521 Species:Mus musculus
Sequence 2:NP_477096.1 Gene:Rh5 / 34615 FlyBaseID:FBgn0014019 Length:382 Species:Drosophila melanogaster


Alignment Length:403 Identity:128/403 - (31%)
Similarity:205/403 - (50%) Gaps:55/403 - (13%)


- Green bases have known domain annotations that are detailed below.


Mouse     1 MDSPSGPR--VLSSLTQDPSFTTSPALQGIWNGTQNVSVRAQLLSVSPTTSAHQA-AAWVPFPTV 62
            ::.||||:  |..||.....|   |...|.                 |....|.. |.|..|...
  Fly     3 INGPSGPQAYVNDSLGDGSVF---PMGHGY-----------------PAEYQHMVHAHWRGFREA 47

Mouse    63 DVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMFIINLAVSDFLMSVTQAPVFF 127
            .:..||.:.:..::|:  |:.:.||..||:.|..::.||||:|:.|:|||:.|..| .|..|.:.
  Fly    48 PIYYHAGFYIAFIVLM--LSSIFGNGLVIWIFSTSKSLRTPSNLLILNLAIFDLFM-CTNMPHYL 109

Mouse   128 ASSLYKKWLFGETGCEFYAFCGAVFGITSMITLTAIAMDRYLVITRPLATIGRGSKRRTALVLLG 192
            .::.....:.|:.||:.||..|.:.|:.:.||...||.|||..|:.|:.  ||.|..:..|::|.
  Fly   110 INATVGYIVGGDLGCDIYALNGGISGMGASITNAFIAFDRYKTISNPID--GRLSYGQIVLLILF 172

Mouse   193 VWLYALAWSLPPFFG-WSAYVPEGLLTSCSWDYMTFTPQVRAYTMLLFCFVFFLPLLIIIFCYIF 256
            .||:|..:|:.|.|. |..|.|||.||:||:||:|.|.:.|.:...:|.:.:.:|:.:|:..|..
  Fly   173 TWLWATPFSVLPLFQIWGRYQPEGFLTTCSFDYLTNTDENRLFVRTIFVWSYVIPMTMILVSYYK 237

Mouse   257 IFRAIRETGRACEGCGESPLRQRRQWQRLQS------------EWKMAKVALIVILLFVLSWAPY 309
            :|..:|        ..|..|.::.:...::|            |.::||.|||:.:||:|:|.||
  Fly   238 LFTHVR--------VHEKMLAEQAKKMNVKSLSANANADNMSVELRIAKAALIIYMLFILAWTPY 294

Mouse   310 STVALVAFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPCLGV-----LL 369
            |.|||:...|...::||::|.:|.:..|:.:..:|.:||.:|||||:.:.:.||.||:     ..
  Fly   295 SVVALIGCFGEQQLITPFVSMLPCLACKSVSCLDPWVYATSHPKYRLELERRLPWLGIREKHATS 359

Mouse   370 GVS-GQRSHPSLS 381
            |.| ||.|..|:|
  Fly   360 GTSGGQESVASVS 372

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Opn4NP_038915.1 7tm_GPCRs 70..358 CDD:475119 100/300 (33%)
TM helix 1 72..96 CDD:410628 7/23 (30%)
TM helix 2 105..127 CDD:410628 9/21 (43%)
TM helix 3 143..165 CDD:410628 7/21 (33%)
TM helix 4 188..204 CDD:410628 6/15 (40%)
TM helix 5 232..255 CDD:410628 4/22 (18%)
TM helix 6 292..314 CDD:410628 13/21 (62%)
TM helix 7 326..351 CDD:410628 7/24 (29%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 445..486
Rh5NP_477096.1 7tmA_photoreceptors_insect 54..343 CDD:320207 100/301 (33%)
TM helix 1 54..80 CDD:320207 7/27 (26%)
TM helix 2 87..112 CDD:320207 9/25 (36%)
TM helix 3 124..154 CDD:320207 12/29 (41%)
TM helix 4 164..184 CDD:320207 6/19 (32%)
TM helix 5 212..241 CDD:320207 6/28 (21%)
TM helix 6 271..301 CDD:320207 16/29 (55%)
TM helix 7 311..336 CDD:320207 7/24 (29%)
Blue background indicates that the domain is not in the aligned region.

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