DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tncb and CG9500

DIOPT Version :9

Sequence 1:	NP_001299845.1	Gene:	tncb / 30037	ZFINID:	ZDB-GENE-980526-104	Length:	1811	Species:	Danio rerio
Sequence 2:	NP_609018.3	Gene:	CG9500 / 33888	FlyBaseID:	FBgn0031804	Length:	292	Species:	Drosophila melanogaster

Alignment Length:	292	Identity:	100/292 - (34%)
Similarity:	143/292 - (48%)	Gaps:	40/292 - (13%)

- Green bases have known domain annotations that are detailed below.

Zfish  1529 LSFESADGVVKEVVLSPTA--------TFYSM-------SQLTASTEYTVKLQAIAGPKRSRVIS 1578
            |||.|.:.:..|...:.||        :.|.:       :|..||||...|            .|
  Fly    13 LSFYSTEAMDSESFQNDTAIRNKPELKSLYKLVLALLEENQSNASTENIQK------------SS 65

Zfish  1579 TVFLTIGVLYKHPKDCSQALLNGDTTSGLYTIYLRGDESQPLQVYCDMTTDGGGWIVFVRRQSGK 1643
            :...|.|:..::|..|.    ......|:||:.:.|  .:|.||.||....|.||.|..||.|.|
  Fly    66 SDLNTTGLSGRYPSQCP----TYPPAHGIYTVQVLG--LKPFQVSCDAEIAGTGWTVMARRTSNK 124

Zfish  1644 VEFFRNWKNYTAGFGDLNDEFWLGLSNLHKITSFGQYELRVDLRD-KGESAYAQYDKFSI-SEPR 1706
            :.|||:|..|..|||.|:.:|::||..||.||....:||.:.|.| :|::.||.||:..| ||.:
  Fly   125 LNFFRSWAEYKNGFGQLDGDFFIGLDKLHAITKSQPHELYIHLEDFEGQTRYAHYDEIFIESENK 189

Zfish  1707 ARYKVHVGGYSGTAGDSMTYHHGRPFSTYDNDNDIAVTNCALSYKGAFWYKNCHRVNIMGRY--G 1769
            ......:|.::|.|||||.::..:.|||:|.|||....|||..|.||:|:.||...|:.|.|  |
  Fly   190 FYAMTKLGEFTGDAGDSMIHNRNQNFSTFDRDNDGWHKNCAEEYVGAWWHLNCTYSNLFGIYVKG 254

Zfish  1770 DNSHS---KGVNWFHWKGHEHSVEFAEMKIRP 1798
            |....   ||:.|..|:...:|.:..:|.:||
  Fly   255 DEGQYFQWKGIVWHSWRTESYSYKVMQMMVRP 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tncb	NP_001299845.1	DnaJ	<471..>544	CDD:333066
		fn3	689..760	CDD:306538
		fn3	778..858	CDD:306538
		fn3	868..948	CDD:306538
		FN3	958..1047	CDD:238020
		fn3	1050..1128	CDD:306538
		fn3	1140..1215	CDD:306538
		fn3	1231..1303	CDD:306538
		fn3	1323..1400	CDD:306538
		fn3	1410..1482	CDD:306538
		fn3	1498..1570	CDD:306538	14/55 (25%)
		FReD	1589..1798	CDD:238040	81/215 (38%)
CG9500	NP_609018.3	FReD	76..287	CDD:238040	83/217 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100073
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.710