Protein Alignment TBX21 and byn

DIOPT Version :9

• Sequence 1: NP_037483.1
• Gene: TBX21 / 30009
• HGNCID: 11599
• Length: 535
• Species: Homo sapiens
• Sequence 2: NP_524031.2
• Gene: byn / 39349
• FlyBaseID: FBgn0011723
• Length: 697
• Species: Drosophila melanogaster
• Alignment Length: 486
• Identity: 154/486 - (31%)
• Similarity: 208/486 - (42%)
• Gaps: 109/486 - (22%)

Human    88 GAGESFPPPADAEGYQPGEGYAAPDPRAGLYPGPREDYALPAGLEVSG----------------- 135
            |||...|......|:..|.|.......:|            .|..|||
  Fly    32 GAGSGSPQHVTHNGHGHGHGLGGVAAVSG------------GGASVSGNGGHRVVGGAGSPNELD 84

Human   136 -KLRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRY 199
             .||::|::..||.:|.....|||:||.||||||.:..:.:||:|.:.|.:.::.|.:|.|.|:|
  Fly    85 RNLRISLDDRELWLRFQNLTNEMIVTKNGRRMFPVVKISASGLDPAAMYTVLLEFVQIDSHRWKY 149

Human   200 QSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLH 264
            .:|:||..|||| ..|.|.:||||:|||.|||||::.:||.|:||||    ..|....|:|.|||
  Fly   150 VNGEWVPGGKAE-VPPSNPIYVHPESPNFGAHWMKEPISFAKVKLTN----KTNGNGQIMLNSLH 209

Human   265 KYQPRLHIVEVNDGEPEAACNASNTHIFT--FQETQFIAVTAYQNAEITQLKIDNNPFAKGF--- 324
            ||:||:|:|.|         .:...|:.|  |.||||||||||||.|:|.|||..|||||.|
  Fly   210 KYEPRVHLVRV---------GSEQRHVVTYPFPETQFIAVTAYQNEEVTSLKIKYNPFAKAFLDA 265

Human   325 RENFESMYTSVDTSIPSPPGPNCQFLGGDHYSPLLPNQYPVPSRFYPDLPGQAKDVVPQAYWLGA 389
            :|..:::|.. ||                ||..|:|     |...|...........|    |..
  Fly   266 KERPDTLYPH-DT----------------HYGWLIP-----PPTHYTAAAAAVAAPPP----LSI 304

Human   390 PRDHSYEAEFRAVSMKPAFLPSAPGPTMSYYR--GQEVLAPGAGWPVAPQYPPKMGPASWFRPMR 452
            .:.|...|...:||...:..||:.|....|.|  ....:||..   ..|...|::...|
  Fly   305 AQSHGLVASCPSVSSAESVGPSSGGSCDRYGRSLSSRSVAPTR---TTPYSRPRVVSGS------ 360

Human   453 TLPMEPGPGGSEGR----GPEDQGPPLVWT--------EIAPIRPESSDSGLGEGDSKRRRVSPY 505
                  |..||.|.    .|:....|...|        .::.....||..|:|...|.....|.|
  Fly   361 ------GSNGSAGNASSTSPQPPSAPQTPTSLHSTSTGSVSTSVSSSSGGGIGSAPSTGCFSSSY 419

Human   506 PSSG----DSSSPAGAPS-PFDKEAEGQFYN 531
            ..||    |:|..|...| |...::.|.::|
  Fly   420 AQSGFMSVDASPTASVFSYPSSWQSNGNYWN 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBX21	NP_037483.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..62
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	83..109		7/20 (35%)
		T-box_TBX21	136..326	CDD:410329	93/194 (48%)
		T-box_assoc	<394..525	CDD:406561	34/149 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	449..535		23/100 (23%)
byn	NP_524031.2	TBOX	86..268	CDD:238106	93/195 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810