Protein Alignment TBX21 and Doc3

DIOPT Version :9

• Sequence 1: NP_037483.1
• Gene: TBX21 / 30009
• HGNCID: 11599
• Length: 535
• Species: Homo sapiens
• Sequence 2: NP_648280.1
• Gene: Doc3 / 39036
• FlyBaseID: FBgn0035954
• Length: 424
• Species: Drosophila melanogaster
• Alignment Length: 455
• Identity: 152/455 - (33%)
• Similarity: 202/455 - (44%)
• Gaps: 113/455 - (24%)

Human   111 PDPRAGLYPG---------PREDYALPAGLEVSGKLRVALNNHLLWSKFNQHQTEMIITKQGRRM 166
            |||..||.|.         |.....||      |.:...|.|:.||.:|:...|||||||.||||
  Fly    30 PDPLCGLLPNFAGHFMPPPPPPQPTLP------GDVEAKLENNELWQQFHSIGTEMIITKCGRRM 88

Human   167 FPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAH 231
            ||.:..:::|||..:.|.:.:::|.:....:::...:||..|.||...| .|:|:||:||.||.|
  Fly    89 FPSMRVSLSGLEEEASYCVLLEMVPIGDCRYKFSGSQWVPAGGAEPQSP-QRMYLHPESPATGKH 152

Human   232 WMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVND-GE----PEAACNASNTHI 291
            |..|.:.|.|:|||||...:|.   .|||.|:||||||||::..:| |:    |:.|
  Fly   153 WQSQALLFSKVKLTNNTLDNNG---HIVLASMHKYQPRLHVIRTSDLGQIPWAPQQA-------- 206

Human   292 FTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSVDTSIPSPPGPNCQFLGGDHYS 356
            |.|.||:|||||||||..||:||||||||||||||:.:|.........|.|..|....:
  Fly   207 FIFPETEFIAVTAYQNDRITKLKIDNNPFAKGFRESGQSRCKRKINDSPPPTQPEANQV------ 265

Human   357 PLLPNQYPVPS------RFYPDLP----GQAKDVVP--QAYWLGAPRDHSYEAEFRAVSMKPAFL 409
                ::.||.|      |...:.|    .|:...||  :.|.|.|     .||.|        ::
  Fly   266 ----DRSPVTSPLAKRLRLVEEFPQHHHHQSHHSVPMQRHYLLDA-----LEANF--------YV 313

Human   410 PSAPGPTMSYYRGQEVLAPGAGWPVAPQYPPKMGPAS--------------------------WF 448
            |:.|.|.:.|.|     ..|..:|.....||  .|||                          :.
  Fly   314 PAPPPPAIEYAR-----HIGGAYPSWAYTPP--SPASSVSSSSAGSTSGESAADREADADADTFV 371

Human   449 RPMRTLPMEPGPGGSEGRGPEDQGPPLVWTEIAPIRPESSDSGLGEGDSKRRRVSPYPSSGDSSS 513
            ..:.|.|..|.|          ..||:..|..|| ...|||..:.:  .||...|.....|.|||
  Fly   372 DVVGTAPAAPPP----------PSPPVPATATAP-ASSSSDPTMAK--PKRSSFSISDILGTSSS 423

Human   514  513
              Fly   424  423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBX21	NP_037483.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..62
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	83..109
		T-box_TBX21	136..326	CDD:410329	91/194 (47%)
		T-box_assoc	<394..525	CDD:406561	34/146 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	449..535		19/65 (29%)
Doc3	NP_648280.1	TBOX	58..245	CDD:238106	93/198 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141552
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840