Protein Alignment TBX21 and H15

DIOPT Version :9

• Sequence 1: NP_037483.1
• Gene: TBX21 / 30009
• HGNCID: 11599
• Length: 535
• Species: Homo sapiens
• Sequence 2: NP_608926.2
• Gene: H15 / 33769
• FlyBaseID: FBgn0016660
• Length: 660
• Species: Drosophila melanogaster
• Alignment Length: 521
• Identity: 154/521 - (29%)
• Similarity: 207/521 - (39%)
• Gaps: 155/521 - (29%)

Human    60 GGALVPAPPSRFLGAYAYPPRPQAAGFPGAGESFPPPADAEGYQPGEGYAAPDPRAGLYPGPRED 124
            |.|..|:||         ||.|..:           |.:.|...|.|. .|..|...:......|
  Fly   229 GAAATPSPP---------PPPPSQS-----------PEELERLSPEES-PAQQPTPKIVGSCNCD 272

Human   125 YALPAGLEVSGKLRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAG----LEPTSHYRM 185
            ...|        ::..|....||.||::..|||||||.||||||.:..:.:|    ::|...|.:
  Fly   273 DLTP--------VQCHLETKELWDKFHELGTEMIITKSGRRMFPTVRVSFSGPLRQIQPADRYAV 329

Human   186 FVDVVLVDQHHWR--YQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGKLKLTNNK 248
            .:|||.:|...:|  |....|:..|||: ..|.:|:|.|||.|.:.....:|.|||.|:|||||:
  Fly   330 LLDVVPLDSRRYRYAYHRSSWLVAGKAD-PPPPSRIYAHPDCPLSPEALRKQVVSFEKVKLTNNE 393

Human   249 GASNNVTQMIVLQSLHKYQPRLHIVEVNDGE-----PEAACNASNTHIFTFQETQFIAVTAYQNA 308
               .:.:..:||.|:|:||||:|:|.::.|:     |:...:..: ..|.|.||.|.|||||||.
  Fly   394 ---MDKSGQVVLNSMHRYQPRIHLVRLSHGQSIPGSPKELQDMDH-KTFVFPETVFTAVTAYQNQ 454

Human   309 EITQLKIDNNPFAKGFRENFESMYTSVDTSIPSPPGPNCQFLGGDHYSPLLPNQYPVPSRFYPD- 372
            .||:||||:||||||||::  |..:..|..      |...|....|       ....|.||:||
  Fly   455 LITKLKIDSNPFAKGFRDS--SRLSDFDRD------PMDAFFFDQH-------MRTAPLRFFPDP 504

Human   373 ----LPGQAKDVVPQAYWLGAPRDH------SYEAE------FRAVSMKPAFLPSAPGPTMSYYR 421
                |..|..|....|. |...|.|      |...|      ::..:..|   |..|.|.:|.::
  Fly   505 LMSQLTPQEADAASMAL-LEKARQHLQMFGRSPYTEMLLPHLYQRSAAPP---PPPPAPHLSAFQ 565

Human   422 --------------------GQEVLA-PGAGWPVAPQYPPKMGPASWFRPMRTLPMEPGPGGSEG 465
                                .|..|| ..||....|  ||.|..|
  Fly   566 LGMWQQQWPQLTAGFLASANQQAALALAAAGANRTP--PPSMAVA-------------------- 608

Human   466 RGPEDQGPPLVWTEIAPIRPESSDSGLGEGDSKRR--------RVSPY---------PSSGDSSS 513
                   ||      ||..|.|| .|....|.:.|        |.|||         |:|..:.|
  Fly   609 -------PP------APATPTSS-CGSASPDLRARPQLNHYPQRFSPYQVPQHQASPPASNRAES 659

Human   514 P 514
            |
  Fly   660 P 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBX21	NP_037483.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..62		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	83..109		4/25 (16%)
		T-box_TBX21	136..326	CDD:410329	85/200 (43%)
		T-box_assoc	<394..525	CDD:406561	35/165 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	449..535		18/83 (22%)
H15	NP_608926.2	TBOX	276..475	CDD:238106	87/213 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141538
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740