| Sequence 1: | NP_219491.1 | Gene: | GZMH / 2999 | HGNCID: | 4710 | Length: | 246 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_649734.2 | Gene: | Sp7 / 40918 | FlyBaseID: | FBgn0037515 | Length: | 391 | Species: | Drosophila melanogaster |
| Alignment Length: | 264 | Identity: | 76/264 - (28%) |
|---|---|---|---|
| Similarity: | 132/264 - (50%) | Gaps: | 36/264 - (13%) |
- Green bases have known domain annotations that are detailed below.
|
Human 14 PGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKR--CGGILVRKDFVLTAAHC--------QGS 68
Human 69 SINVTLGAH----------NIKEQERTQQFIPVKRPIPHPAYNP--KNFSNDIMLLQLERKAKWT 121
Human 122 TAVRPLRLP--SSKAQVKPGQLCSVAGWGYVSMSTLATTLQEVLLTVQKDCQCERLF--HGNYSR 182
Human 183 ATEICVGDPKKTQTGFKGDSGGPLVCKDVAQ-----GILSYGNKKGTP--PGVYIKVSHFLPWIK 240
Human 241 RTMK 244 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| GZMH | NP_219491.1 | Tryp_SPc | 21..242 | CDD:238113 | 74/253 (29%) |
| Mediates the preference for acidic residues at the P3' and P4' sites | 46..48 | 1/1 (100%) | |||
| Sp7 | NP_649734.2 | CLIP | 31..84 | CDD:463440 | |
| Tryp_SPc | 137..388 | CDD:238113 | 74/253 (29%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||