Protein Alignment SLC2A8 and sut2

DIOPT Version :9

• Sequence 1: NP_055395.2
• Gene: SLC2A8 / 29988
• HGNCID: 13812
• Length: 477
• Species: Homo sapiens
• Sequence 2: NP_524732.1
• Gene: sut2 / 44269
• FlyBaseID: FBgn0028562
• Length: 491
• Species: Drosophila melanogaster
• Alignment Length: 449
• Identity: 121/449 - (26%)
• Similarity: 196/449 - (43%)
• Gaps: 78/449 - (17%)

Human    66 DAAASWFGAVVTLGA------------AAGGVLGGW----LVDRAGRKLSLLLCSVPFVAGFAVI 114
            |..|:.:..:||.|.            ..||:.|..    |.|:.|||..|::.||.||....:.
  Fly    54 DILANEYDTIVTAGQLDILWTSIVSIYLIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILF 118

Human   115 T---AAQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLA---- 172
            |   ||:.:.||:.||.|.|:|..:.....|:|:.|.|...:.|.:|....:.|..|||||
  Fly   119 TWCRAAKSLEMLMTGRFLGGIASALIFTAQPMYLLESAPSELSGSVGVFTCIGVTGGILLAQVAT 183

Human   173 --YLAGWVLEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMA--ALRFLWGSEQGWE 233
              :|.|....|.:......:.....|:|:.:.||:||:|.. |:|..|.:  ||..|.|.....|
  Fly   184 LSHLLGSERLWPYALSFYSLLVMASLVLLWWFPESPRWLYL-HKRDSAASEKALLRLRGRNTEEE 247

Human   234 ------------DPPIGAEQSFHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEA 286
                        :....:|.|...::||...::.|.::..|..|.|||||:||:.||:.:|...|
  Fly   248 VHQELLEMKATLEAKSSSEVSSLCSVLRNSELWLPLLLVCSFQATQQLSGINAIFFYSLSILTNA 312

Human   287 KFKDSSLA--SVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSA--FGAYFKLTQGGP 347
            .|.|.:..  ::.:|...:..:.:..|::.|..||.|:::|..:...:..|  .|.:|
  Fly   313 GFSDGAATWLNLGIGSFNLCTSLLGPLLIRRFPRRPLMMISCSMCALALLAMSLGLFF------- 370

Human   348 GNSSHVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGI 412
                         .:..:::| |.:.....:..||.||.:|.|||.:.:.||:.....:.||..:
  Fly   371 -------------LERSESTV-LTYFCAAFILTFILGFQLGLGPIAYFIGSELLEDSPRPVAMSM 421

Human   413 CVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAF------CIFSVLFTLFCVPETKGK 465
            ..|.:|:..|||...|..|..|       |.:.||      ||:.:|.|...:|||:|:
  Fly   422 GSLFSWIGNFLVGMCFPLLQSV-------WSSFAFIPCMCVCIYCLLLTWRYLPETRGR 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC2A8	NP_055395.2	Dileucine internalization motif. /evidence=ECO:0000250|UniProtKB:Q9JJZ1	12..13
		xylE	36..472	CDD:182225	121/449 (27%)
		MFS	38..459	CDD:119392	117/441 (27%)
		Monosaccharide binding. /evidence=ECO:0000250|UniProtKB:P11166	267..273		5/5 (100%)
sut2	NP_524732.1	Sugar_tr	23..473	CDD:278511	120/447 (27%)
		MFS	76..466	CDD:119392	112/418 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144066
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840