Protein Alignment SLC2A8 and sut4

DIOPT Version :10

• Sequence 1: XP_047279239.1
• Gene: SLC2A8 / 29988
• HGNCID: 13812
• Length: 599
• Species: Homo sapiens
• Sequence 2: NP_523675.1
• Gene: sut4 / 36055
• FlyBaseID: FBgn0028560
• Length: 444
• Species: Drosophila melanogaster
• Alignment Length: 458
• Identity: 143/458 - (31%)
• Similarity: 242/458 - (52%)
• Gaps: 47/458 - (10%)

Human   144 LGTSTGPLSPLPLPSGRARGPGSFTSEPAGSGWRGRMGCGFGAPSSAAARLQAVVTLGAAAGGVL 208
            ||...|...|:   ....:...::...|..:.| |.:|              :::|||||...:.
  Fly    20 LGAVIGWSGPV---ENEVKNSNAYNFTPRQTEW-GLVG--------------SLMTLGAAFSCIP 66

Human   209 GGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYP 273
            .|.|:.:.|||.::|:...||..|:.:|..|..:.|||.||.:.|...|...:..|:|::|||..
  Fly    67 VGVLIGKIGRKTTMLILLPPFFIGWLLILLASHIAMLLLGRFVVGFCGGAFCVTCPMYVTEIAQV 131

Human   274 AVRGLLGSCVQLMVVVGILLAYLAGWVLEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQ 338
            ..||.:|...||::|.|||.|::.|..::..:..:...:.|.:..:||.||||:|.||..:.:.:
  Fly   132 QYRGTMGCFFQLLIVFGILYAFVVGGFVKTFYFNIACAILPVIFFVLMIFMPESPIFLAQKGKAE 196

Human   339 EAMAALRFLWG--SEQGWEDPPIGAEQSFHLA----LLRQPGIYKPFIIGVSLMAFQQLSGVNAV 397
            :|..:|:||.|  ::...|...:.||.....|    :|.:....|...:.:.||.|||::|:||:
  Fly   197 KAEKSLKFLRGKDADVSGELKEMSAEGQKEKASVGKILCRRITLKGLFLSIGLMLFQQMTGINAI 261

Human   398 MFYAETIFEEA-KFKDSSLASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAY 461
            :||:..|||.| ...:..:::::||::|.:.|.::.|::::.||::||::|..:|..||.....|
  Fly   262 IFYSTFIFETAGSTLEPRISTIIVGIVQAIATIISILVIEKVGRKILLLVSACMMGISTLIMALY 326

Human   462 FKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLH 526
            |.:..                      ..|:.|||:.::|:||.||::|:||:|||:|:|:|...
  Fly   327 FGMLM----------------------KSGVGWLALIAVCVFIIGFSLGFGPVPWLMMAELFAED 369

Human   527 VKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQ 591
            ||.:|..|...|||..||:||..|..|.:::.....|.:...|.:.:.:|.||.:||||||||.:
  Fly   370 VKALAGSIAGTTNWCFAFIVTLLFPVLNDIIGATACFAIFFGFAVAAFVFILFLIPETKGKTLNE 434

Human   592 ITA 594
            |.|
  Fly   435 IQA 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC2A8	XP_047279239.1	PHA03307	3..>196	CDD:223039	8/51 (16%)
		MFS	36..591	CDD:475125	141/453 (31%)
sut4	NP_523675.1	MFS_GLUT6_8_Class3_like	7..434	CDD:340916	141/453 (31%)