Protein Alignment SLC39A3 and Zip89B

DIOPT Version :9

• Sequence 1: NP_653165.2
• Gene: SLC39A3 / 29985
• HGNCID: 17128
• Length: 314
• Species: Homo sapiens
• Sequence 2: NP_536747.2
• Gene: Zip89B / 41975
• FlyBaseID: FBgn0038412
• Length: 495
• Species: Drosophila melanogaster
• Alignment Length: 362
• Identity: 108/362 - (29%)
• Similarity: 173/362 - (47%)
• Gaps: 63/362 - (17%)

Human     4 LLVAKILCMVGVFFFMLLGSLLPVKIIE----TDFEKAHRSKKILSLCNTFGGGVFLATCFNALL 64
            :||||:..||.:|....:...:|..:..    |:.:...||..::.....|||||.|||.|..||
  Fly    52 VLVAKVTAMVVLFCASAICGSIPFLLNRCYRWTENQTNARSAIVVKCLLYFGGGVLLATTFLHLL 116

Human    65 PAVREKLQKVLSLGHI-STDYPLAETILLLGFFMTVFLEQLILTF----RKE------------- 111
            |.|:|.::::...|.| ...:||||.::..|||:..|:|:.:.|:    :|:
  Fly   117 PEVQEVVEELQECGIIGELTFPLAELLMCCGFFLMYFIEEAMHTYVHHHQKDEAGAAFERGHSIR 181

Human   112 -----KPS----------------FIDLETFNAGSDVGSDSE---YESPFMGGARGHALYVEPHG 152
                 ||:                ..:|.|.:..:.:.:|.|   :.:.....|.||. :...||
  Fly   182 NSHLLKPTEGNATTPTAPPAPLAGTAELGTLSVQNLLQNDLEQQKFATKPQQQANGHG-HSHGHG 245

Human   153 HGPS-LSV------QGLSRASPVRLLSLAFALSAHSVFEGLALGLQEEGEKVVSLFVGVAVHETL 210
            ||.| |.|      .|...||.:|.|.:..|||.|.:|||:|:||:.....|..:|..|:.|:.:
  Fly   246 HGHSHLPVIADDADAGDMLASSLRGLFIVSALSLHELFEGMAIGLESSASSVWFMFGAVSAHKLV 310

Human   211 VAVALGISM--ARSAMPLRDAAKLAVTVSAMIPLGIGLGLGIESAQGVPG-SVASVLLQGLAGGT 272
            :|..:|:.:  ||:.|.|  |....:|.:.:.|||||:|:.|...:...| |:.|.:|||.|.||
  Fly   311 LAFCVGVELIVARTRMLL--AVLYVLTFAVVSPLGIGIGILINHGEETSGPSLVSAILQGFACGT 373

Human   273 FLFITFLEILAKELEEKSDRLLKVLFLVLGYTVLAGM 309
            .:::.|.|||:|    ....|...|.|.:|:.|:.|:
  Fly   374 LIYVVFFEILSK----NRSGLRAYLALFVGFLVMFGL 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC39A3	NP_653165.2	Zip	5..309	CDD:396884	107/359 (30%)
Zip89B	NP_536747.2	Zip	53..406	CDD:280666	107/359 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1558
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H44230
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D471714at33208
OrthoFinder	1	1.000	-	-		FOG0000574
OrthoInspector	1	1.000	-	-		mtm8626
orthoMCL	1	0.900	-	-		OOG6_100840
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X561
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.680