DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment NRBF2 and CG42554

DIOPT Version :10

Sequence 1:NP_110386.2 Gene:NRBF2 / 29982 HGNCID:19692 Length:287 Species:Homo sapiens
Sequence 2:NP_001163314.1 Gene:CG42554 / 8674073 FlyBaseID:FBgn0260756 Length:213 Species:Drosophila melanogaster


Alignment Length:282 Identity:62/282 - (21%)
Similarity:107/282 - (37%) Gaps:101/282 - (35%)


- Green bases have known domain annotations that are detailed below.


Human     7 PLNLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEAMK---LTQSEQA--HLSLELQRDSHMK 66
            ||||||...||::|.:...:|||||...:.:..|:.:|.|   |.:|::.  .|:|:.||  .::
  Fly     5 PLNLAHFHERRSERFIRNHRYEEAIKALETSLIYMQDAQKRVALPKSKEVLDTLTLDFQR--KLR 67

Human    67 QLLLIQERWKRAQREERLKAQQ--NTDKDAAAHLQTSH----KPSAEDAEGQSPLSQKYSPSTEK 125
            |:             |..|.|.  |..||.|...:||.    :|.|..:.|....:|..:.:.:|
  Fly    68 QI-------------EMRKTQHGLNKLKDYAPLKETSPMLPLRPEAGASGGAGGSAQSVAKAIDK 119

Human   126 CLPEIQGIFDRDPDTLLYLLQQKSEPAEPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENE 190
            .:.:    ||                         .|...:::.:.::.:|..:.|:|.|     
  Fly   120 TVQD----FD-------------------------AKFTSSLVAKASSTLAHSEPHMETL----- 150

Human   191 RLRKENKQLKAEKARLLKGPIEKELDVDADFVETSELWSLPPHAETATASSTWQKFAANTGKAKD 255
                    .|::.|:     .|:|.|                         |..:..|.:|   |
  Fly   151 --------KKSDSAQ-----EEQEHD-------------------------TCDQRLAGSG---D 174

Human   256 IPIPNLPPLDFPSPELPLMELS 277
            :.:|:|.||:.||.:..|...|
  Fly   175 LDLPSLAPLELPSFDYSLFTSS 196

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NRBF2NP_110386.2 NRBF2_MIT 4..86 CDD:465368 25/83 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 83..122 12/44 (27%)
NRBF2 89..284 CDD:430345 35/193 (18%)
Nuclear receptor interaction motif 141..145 0/3 (0%)
CG42554NP_001163314.1 NRBF2_MIT 4..>64 CDD:465368 21/58 (36%)

Return to query results.
Submit another query.