| Sequence 1: | NP_001100254.1 | Gene: | Lgr5 / 299802 | RGDID: | 1307733 | Length: | 907 | Species: | Rattus norvegicus |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001285192.1 | Gene: | Lgr4 / 5740505 | FlyBaseID: | FBgn0085440 | Length: | 809 | Species: | Drosophila melanogaster |
| Alignment Length: | 921 | Identity: | 214/921 - (23%) |
|---|---|---|---|
| Similarity: | 321/921 - (34%) | Gaps: | 272/921 - (29%) |
- Green bases have known domain annotations that are detailed below.
|
Rat 6 VRMLLSLLALLQ------LVAAGSPPRPDTMPRGCPSYCHCELDGRMLLR-------VDCSDLGL 57
Rat 58 SELPSNLSVFTSYLDLSMNNISQLPASLLHRLRFLE---------------ELRLAGNALTHIPK 107
Rat 108 GAFAGLHSLKVLMLQNNQLRQVPEEALQNLRSLQSLRLDANHISYVPPSCFSGL--HSLRHLWLD 170
Rat 171 DNALTDVPVQAFRSLSALQAMTLALNKIHHIADHAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHS 235
Rat 236 LETLDLNYNNL-----DEFPTAIKTLSNLKELGFHSNNIRSIPERAFVGNPSLITIHFYDNPIQF 295
Rat 296 VGISAFQHLPELRTLTLNGASQITEFPDLTGTATLESLTLTGAKISSLPQTVCDQLPNLQVLDLS 360
Rat 361 YNLLEDLPSLSGCQKLQKIDLRHNEIYEIKGGTFQQLFNLRSLNLARNKIAIIHPNAFSTLPSLI 425
Rat 426 KLDLSSNLLSSFPVTGLHGLTHLKLTGNR--ALQSLIPSANFPELKIIEMPYAYQCCAFGGCENV 488
Rat 489 YKIPNQWNKDDSSSVDDLRKKDAGLFQVQDERDLEDFLLDFEEDLKVLHSVQCSPPPGPFKPCEH 553
Rat 554 LFGSWLIRIGVWTTAVLALSCNALVA----FTVFRTPLYISSIKLLIGVIAVVDILMGVSSAILA 614
Rat 615 VVDTFTFGSFAQHGAWWEGGIGCQIVGFLSIFASESSVFLLTLAALERGFSVKCSSKFEMKAPLS 679
Rat 680 SLKAIILLCVLL----ALTIATVPLL-----GGSEYNASPLCLPLPFGEPSTTGY---MVALVLL 732
Rat 733 NSLCFLIMTIAYTRL----------YCSLEKGELENLWDCSMVKHTALLLFTNCILYCPVAFLSF 787
Rat 788 SSLLNLTFISPEVIKFILLVIVPLPACLNPLLYIVFNPHFKEDM----------GSLGKQTRFWT 842
Rat 843 RAKHPSLLSIN 853 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Lgr5 | NP_001100254.1 | LRRNT | 33..70 | CDD:214470 | 10/43 (23%) |
| LRR 1 | 44..64 | 5/26 (19%) | |||
| LRR 2 | 65..88 | 4/22 (18%) | |||
| leucine-rich repeat | 68..91 | CDD:275380 | 4/22 (18%) | ||
| LRR_RI | 88..372 | CDD:238064 | 72/305 (24%) | ||
| LRR 3 | 89..112 | 8/37 (22%) | |||
| LRR_8 | 92..150 | CDD:290566 | 16/72 (22%) | ||
| leucine-rich repeat | 92..115 | CDD:275380 | 6/37 (16%) | ||
| LRR 4 | 114..136 | 6/21 (29%) | |||
| leucine-rich repeat | 116..139 | CDD:275380 | 6/22 (27%) | ||
| LRR 5 | 137..160 | 6/22 (27%) | |||
| LRR_8 | 138..198 | CDD:290566 | 19/61 (31%) | ||
| leucine-rich repeat | 140..163 | CDD:275380 | 6/24 (25%) | ||
| LRR 6 | 162..184 | 9/21 (43%) | |||
| leucine-rich repeat | 164..187 | CDD:275380 | 9/22 (41%) | ||
| LRR 7 | 186..208 | 7/21 (33%) | |||
| LRR_8 | 188..246 | CDD:290566 | 23/57 (40%) | ||
| leucine-rich repeat | 188..211 | CDD:275380 | 9/22 (41%) | ||
| LRR 8 | 209..232 | 8/22 (36%) | |||
| leucine-rich repeat | 212..235 | CDD:275380 | 8/22 (36%) | ||
| LRR 9 | 233..256 | 11/27 (41%) | |||
| leucine-rich repeat | 236..258 | CDD:275380 | 12/26 (46%) | ||
| LRR_8 | 257..314 | CDD:290566 | 12/56 (21%) | ||
| LRR 10 | 257..279 | 7/21 (33%) | |||
| leucine-rich repeat | 259..282 | CDD:275380 | 6/22 (27%) | ||
| LRR 11 | 281..303 | 0/21 (0%) | |||
| leucine-rich repeat | 283..304 | CDD:275380 | 0/20 (0%) | ||
| LRR 12 | 304..327 | 6/22 (27%) | |||
| leucine-rich repeat | 307..353 | CDD:275380 | 5/45 (11%) | ||
| LRR 13 | 328..350 | 0/21 (0%) | |||
| LRR 14 | 351..375 | 0/23 (0%) | |||
| LRR_8 | 352..410 | CDD:290566 | 10/57 (18%) | ||
| leucine-rich repeat | 354..375 | CDD:275380 | 0/20 (0%) | ||
| leucine-rich repeat | 376..399 | CDD:275380 | 5/22 (23%) | ||
| LRR 15 | 377..396 | 4/18 (22%) | |||
| LRR 16 | 397..420 | 9/22 (41%) | |||
| leucine-rich repeat | 400..423 | CDD:275380 | 8/22 (36%) | ||
| LRR 17 | 422..444 | 4/21 (19%) | |||
| leucine-rich repeat | 445..467 | CDD:275378 | 8/23 (35%) | ||
| LRR 18 | 564..585 | 8/24 (33%) | |||
| 7tm_1 | 575..820 | CDD:278431 | 70/270 (26%) | ||
| Lgr4 | NP_001285192.1 | Ldl_recept_a | 87..124 | CDD:278486 | 11/40 (28%) |
| LRR_RI | <184..397 | CDD:238064 | 75/309 (24%) | ||
| LRR_8 | 188..248 | CDD:290566 | 18/59 (31%) | ||
| leucine-rich repeat | 188..211 | CDD:275380 | 6/22 (27%) | ||
| leucine-rich repeat | 212..235 | CDD:275380 | 6/22 (27%) | ||
| leucine-rich repeat | 238..261 | CDD:275380 | 9/22 (41%) | ||
| LRR_8 | 261..320 | CDD:290566 | 23/58 (40%) | ||
| leucine-rich repeat | 262..285 | CDD:275380 | 9/22 (41%) | ||
| LRR_4 | 284..325 | CDD:289563 | 15/40 (38%) | ||
| leucine-rich repeat | 286..309 | CDD:275380 | 8/22 (36%) | ||
| LRR_4 | 308..348 | CDD:289563 | 17/42 (40%) | ||
| leucine-rich repeat | 310..334 | CDD:275380 | 12/26 (46%) | ||
| leucine-rich repeat | 335..357 | CDD:275380 | 6/46 (13%) | ||
| LRR_8 | 356..416 | CDD:290566 | 28/149 (19%) | ||
| leucine-rich repeat | 358..381 | CDD:275380 | 10/91 (11%) | ||
| LRR_4 | 381..421 | CDD:289563 | 19/60 (32%) | ||
| leucine-rich repeat | 382..405 | CDD:275380 | 8/22 (36%) | ||
| leucine-rich repeat | 406..427 | CDD:275380 | 11/42 (26%) | ||
| 7tm_1 | 483..741 | CDD:278431 | 70/271 (26%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG2087 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||