Protein Alignment DONSON and hd

DIOPT Version :10

• Sequence 1: NP_060083.1
• Gene: DONSON / 29980
• HGNCID: 2993
• Length: 566
• Species: Homo sapiens
• Sequence 2: NP_649531.1
• Gene: hd / 40642
• FlyBaseID: FBgn0086695
• Length: 568
• Species: Drosophila melanogaster
• Alignment Length: 618
• Identity: 194/618 - (31%)
• Similarity: 278/618 - (44%)
• Gaps: 130/618 - (21%)

Human    14 KPPEVVRLRRKRARSRGAAA-------SPPRELTEPAARRAALVAGLPLRPFPAAGGRGGGSGGG 71
            :|.:.::|:|.:.:....||       ..||...:...:...|.|.|
  Fly    13 RPDDFIKLQRLKQKKNKLAARVSNNNNRRPRHQVDETDKSKLLEAKL------------------ 59

Human    72 PAAARRNPFA---------RLDNRPRVAAEPPDGPA-----REQPEAPVPFLDSNQENDLLWEEK 122
             |..|:||||         |:|  |::|...|...|     ||.|..|.|.....|:.|
  Fly    60 -AQKRKNPFAKSTADAKKLRVD--PQLADLEPVVTASSCFVRETPTRPAPAKFVLQKYD------ 115

Human   123 FPERTTVTELPQTSHVSFSEPDIPS------------SKSTELPVDWSIKTRLLF--TSSQPFTW 173
                      ||.....|..|.|.:            ..:..||||||:|||..|  .:..|
  Fly   116 ----------PQAFAKLFQHPQINAEDEDDAELAARQKHTAHLPVDWSLKTRARFFCPTELP--- 167

Human   174 ADHLKAQEEAQGLVQHCRATEVTLPKSIQDPKLSSELRCTFQQSLIYWLHPALSWLPLFPRIGAD 238
            |..||..:.|.||....|..:....:|..|  :|...|  |.|...||.||.|.||.|:||...:
  Fly   168 AIQLKTSQLASGLTSFVRCMDPQRTESTLD--ISDATR--FNQCNYYWQHPHLPWLTLYPRTAKE 228

Human   239 R--KMAGKTSPWSNDATLQHVLMSDWSVSFTSLYNLLKTKLCPYFYVCTYQFTVLFRAAGLAGSD 301
            .  .:.|:..        :..|..:|..||..|:.||:.:.|||||:|...|||||||||:.|..
  Fly   229 NVGVVVGERE--------RKALAEEWDFSFRGLFQLLRARQCPYFYLCANTFTVLFRAAGVGGRP 285

Human   302 LITALISPTTRGLREAMRNEGIEFSLPLIKE-SGHK-----KETASGTSLG--YGEE---QAISD 355
            ...||::|:|||:|:|:|.||||||:||..: ||:.     .|.::.||||  .||:   .|..|
  Fly   286 ESHALVTPSTRGMRQALRQEGIEFSMPLKSDNSGNAHDNSFNEESTTTSLGPEAGEDAPPPAQED 350

Human   356 EDEEESFSWLEEMGVQDK-IKKPDILSIKLRKEK-HEVQMDHRPESVVLVKGINTFTLLNFLINS 418
            ||::|  .|||.:||.:: :::  |.|...||:: .|::.|....|::||.|:......::|:|:
  Fly   351 EDDDE--DWLESLGVDERELRR--IQSSHARKQQAAEMREDFSDNSLLLVDGVECQGFFSYLLNA 411

Human   419 KSLVATSGPQAGLPPTLLSPVAFRGATMQMLKARSVNVKTQALSGYRDQFSLEITGPIMPHSLHS 483
            ||.::|.|..||:||||||||||..||||.|..||..|:...:    |.||::|.|.|:|..|.|
  Fly   412 KSAISTVGRLAGVPPTLLSPVAFPKATMQHLVPRSKKVRLDGV----DYFSIDIKGLILPTFLPS 472

Human   484 LTMLLKSSQSGSFSAVLYPHEPTAVFNICLQMDKVLDMEVV----------------HKELTNCG 532
            :..||..::. .||:.|.....|..|:...|  |:|:....                .:.|:.||
  Fly   473 VAELLSETRQ-MFSSTLASSINTLAFSKATQ--KLLETPETPQSDAEGEDAAGQVFGEQNLSECG 534

Human   533 LHPNTLEQLSQIPLLGKSSLRNVVL-RDYIYNW 564
            |.|..:..:.:........|..|.. ||..|.|
  Fly   535 LLPAVVGSICRTGQHAVGLLERVCYQRDEGYAW 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DONSON	NP_060083.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..110		27/116 (23%)
hd	NP_649531.1	None