Protein Alignment UBQLN1 and Ubqln1

DIOPT Version :10

• Sequence 1: NP_038466.2
• Gene: UBQLN1 / 29979
• HGNCID: 12508
• Length: 589
• Species: Homo sapiens
• Sequence 2: NP_081118.4
• Gene: Ubqln1 / 56085
• MGIID: 1860276
• Length: 582
• Species: Mus musculus
• Alignment Length: 592
• Identity: 524/592 - (88%)
• Similarity: 547/592 - (92%)
• Gaps: 13/592 - (2%)

Human     1 MAESGESGGPPGSQDSAAGAEGAGAPAAAASAEPKIMKVTVKTPKEKEEFAVPENSSVQQFKEEI 65
            ||||.|||||||:|||||.    |.|     ||||||||||||||||||||||||||||||||||
Mouse     1 MAESAESGGPPGAQDSAAD----GGP-----AEPKIMKVTVKTPKEKEEFAVPENSSVQQFKEEI 56

Human    66 SKRFKSHTDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQNRPQDHSAQQTNTAGSNVTTS 130
            |||||||.|||||||||||||||||||||||||||||||||||||||||:||||||..||.||:|
Mouse    57 SKRFKSHIDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQNRPQDNSAQQTNAPGSTVTSS 121

Human   131 STPNSNSTSGSATSNPFGLGGLGGLAGLSSLGLNTTNFSELQSQMQRQLLSNPEMMVQIMENPFV 195
            ..|:||.|||||.::.||:||||||||||||||||||||||||||||||||||||||||||||||
Mouse   122 PAPDSNPTSGSAANSSFGVGGLGGLAGLSSLGLNTTNFSELQSQMQRQLLSNPEMMVQIMENPFV 186

Human   196 QSMLSNPDLMRQLIMANPQMQQLIQRNPEISHMLNNPDIMRQTLELARNPAMMQEMMRNQDRALS 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   187 QSMLSNPDLMRQLIMANPQMQQLIQRNPEISHMLNNPDIMRQTLELARNPAMMQEMMRNQDRALS 251

Human   261 NLESIPGGYNALRRMYTDIQEPMLSAAQEQFGGNPFASLVSNTSSGEGSQPSRTENRDPLPNPWA 325
            ||||||||||||||||||||||||:||||||||||||||||::||.||:||||||||||||||||
Mouse   252 NLESIPGGYNALRRMYTDIQEPMLNAAQEQFGGNPFASLVSSSSSAEGTQPSRTENRDPLPNPWA 316

Human   326 PQTSQSSSASSGTASTVG--GTTGSTASGT-SGQSTTAPNLVPGVGASMFNTPGMQSLLQQITEN 387
            |||||||.||..|.||..  .|:|.||:.| :||||:.|:||||.||||||||||||||||||||
Mouse   317 PQTSQSSPASGTTGSTTNTMSTSGGTATSTPAGQSTSGPSLVPGAGASMFNTPGMQSLLQQITEN 381

Human   388 PQLMQNMLSAPYMRSMMQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQNPDTLS 452
            ||||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   382 PQLMQNMLSAPYMRSMLQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQNPDTLS 446

Human   453 AMSNPRAMQALLQIQQGLQTLATEAPGLIPGFTPGLGALGSTGGSSGTNGSNATPSENTSPTAGT 517
            ||||||||||||||||||||||||||||||||||||.| |::|||||||..:..|||:|:|..||
Mouse   447 AMSNPRAMQALLQIQQGLQTLATEAPGLIPGFTPGLAA-GNSGGSSGTNAPSTAPSEDTNPQGGT 510

Human   518 TEPGHQQFIQQMLQALAGVNPQLQNPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIER 582
            .|||||||||||||||||||||||:||||||||||||||||||||||||||||||||||||||||
Mouse   511 AEPGHQQFIQQMLQALAGVNPQLQSPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIER 575

Human   583 LLGSQPS 589
            |||||||
Mouse   576 LLGSQPS 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UBQLN1	NP_038466.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..35		20/33 (61%)
		Ubl_PLICs	35..107	CDD:340506	70/71 (99%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	110..145		24/34 (71%)
		Interaction with UBXN4. /evidence=ECO:0000269|PubMed:19822669	178..428		227/252 (90%)
		STI1	182..219	CDD:128966	36/36 (100%)
		STI1	212..256	CDD:450205	43/43 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	295..371		55/78 (71%)
		STI1	390..422	CDD:128966	30/31 (97%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	488..520		17/31 (55%)
		UBA_PLICs	546..585	CDD:270582	38/38 (100%)
Ubqln1	NP_081118.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25		19/32 (59%)
		Ubl_PLICs	26..98	CDD:340506	70/71 (99%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	103..136		22/32 (69%)
		Interaction with UBXN4. /evidence=ECO:0000250|UniProtKB:Q9UMX0	169..422		227/252 (90%)
		STI1	173..210	CDD:128966	36/36 (100%)
		STI1	203..247	CDD:450205	43/43 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	286..365		55/78 (71%)
		STI1	384..416	CDD:128966	30/31 (97%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	478..513		21/35 (60%)
		UBA_PLICs	539..578	CDD:270582	38/38 (100%)