Protein Alignment UBQLN1 and Ubqln1

DIOPT Version :10

• Sequence 1: NP_038466.2
• Gene: UBQLN1 / 29979
• HGNCID: 12508
• Length: 589
• Species: Homo sapiens
• Sequence 2: NP_446199.2
• Gene: Ubqln1 / 114590
• RGDID: 620745
• Length: 582
• Species: Rattus norvegicus
• Alignment Length: 592
• Identity: 515/592 - (86%)
• Similarity: 538/592 - (90%)
• Gaps: 13/592 - (2%)

Human     1 MAESGESGGPPGSQDSAAGAEGAGAPAAAASAEPKIMKVTVKTPKEKEEFAVPENSSVQQFKEEI 65
            ||||.|||||||:|||||.         :..||||||||||||||||||||||||||||||||||
  Rat     1 MAESAESGGPPGAQDSAAD---------SGPAEPKIMKVTVKTPKEKEEFAVPENSSVQQFKEEI 56

Human    66 SKRFKSHTDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQNRPQDHSAQQTNTAGSNVTTS 130
            |||||||.|||||||||||||||||||||||||||||||||||||||||:|||||||.|::||:|
  Rat    57 SKRFKSHIDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQNRPQDNSAQQTNTTGNSVTSS 121

Human   131 STPNSNSTSGSATSNPFGLGGLGGLAGLSSLGLNTTNFSELQSQMQRQLLSNPEMMVQIMENPFV 195
            ..|:||.|||.|.::.|||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   122 PAPDSNPTSGPAANSSFGLGGLGGLAGLSSLGLNTTNFSELQSQMQRQLLSNPEMMVQIMENPFV 186

Human   196 QSMLSNPDLMRQLIMANPQMQQLIQRNPEISHMLNNPDIMRQTLELARNPAMMQEMMRNQDRALS 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   187 QSMLSNPDLMRQLIMANPQMQQLIQRNPEISHMLNNPDIMRQTLELARNPAMMQEMMRNQDRALS 251

Human   261 NLESIPGGYNALRRMYTDIQEPMLSAAQEQFGGNPFASLVSNTSSGEGSQPSRTENRDPLPNPWA 325
            ||||||||||||||||||||||||:||||||||||||||||:.||.||:||||||||||||||||
  Rat   252 NLESIPGGYNALRRMYTDIQEPMLNAAQEQFGGNPFASLVSSPSSAEGTQPSRTENRDPLPNPWA 316

Human   326 PQTSQSSSASSGTAS---TVGGTTGSTASGTSGQSTTAPNLVPGVGASMFNTPGMQSLLQQITEN 387
            |||.|||.||..|.|   ||..:.|:..|..:||.|:.||||||.||||||||||||||||||||
  Rat   317 PQTPQSSPASGSTGSTTNTVSTSAGNATSTPAGQGTSGPNLVPGAGASMFNTPGMQSLLQQITEN 381

Human   388 PQLMQNMLSAPYMRSMMQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQNPDTLS 452
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   382 PQLMQNMLSAPYMRSMMQSLSQNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQMQNPDTLS 446

Human   453 AMSNPRAMQALLQIQQGLQTLATEAPGLIPGFTPGLGALGSTGGSSGTNGSNATPSENTSPTAGT 517
            ||||||||||||||||||||||||||||||||||||.| |::||.:||...:..|.|:|:|..|.
  Rat   447 AMSNPRAMQALLQIQQGLQTLATEAPGLIPGFTPGLAA-GNSGGPAGTTAPSTAPGEDTNPQGGA 510

Human   518 TEPGHQQFIQQMLQALAGVNPQLQNPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIER 582
            .|||||||||||||||||||||||:||||||||||||||||||||||||||||||||||||||||
  Rat   511 AEPGHQQFIQQMLQALAGVNPQLQSPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIER 575

Human   583 LLGSQPS 589
            |||||||
  Rat   576 LLGSQPS 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UBQLN1	NP_038466.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..35		18/33 (55%)
		Ubl_PLICs	35..107	CDD:340506	70/71 (99%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	110..145		23/34 (68%)
		Interaction with UBXN4. /evidence=ECO:0000269|PubMed:19822669	178..428		225/252 (89%)
		STI1	182..219	CDD:128966	36/36 (100%)
		STI1	212..256	CDD:450205	43/43 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	295..371		52/78 (67%)
		STI1	390..422	CDD:128966	31/31 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	488..520		12/31 (39%)
		UBA_PLICs	546..585	CDD:270582	38/38 (100%)
Ubqln1	NP_446199.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26		18/33 (55%)
		Ubl_PLICs	26..98	CDD:340506	70/71 (99%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	102..136		22/33 (67%)
		Interaction with UBXN4. /evidence=ECO:0000250|UniProtKB:Q9UMX0	169..422		225/252 (89%)
		STI1	173..210	CDD:128966	36/36 (100%)
		STI1	203..247	CDD:450205	43/43 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	285..365		53/79 (67%)
		STI1	384..416	CDD:128966	31/31 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	481..513		13/32 (41%)
		UBA_PLICs	539..578	CDD:270582	38/38 (100%)