Protein Alignment GYS1 and gys1

DIOPT Version :10

• Sequence 1: NP_002094.2
• Gene: GYS1 / 2997
• HGNCID: 4706
• Length: 737
• Species: Homo sapiens
• Sequence 2: NP_957474.1
• Gene: gys1 / 394155
• ZFINID: ZDB-GENE-040426-1243
• Length: 700
• Species: Danio rerio
• Alignment Length: 693
• Identity: 568/693 - (81%)
• Similarity: 626/693 - (90%)
• Gaps: 13/693 - (1%)

Human     1 MPLNRTLSMSSLPGLEDWEDEFDLENAVLFEVAWEVANKVGGIYTVLQTKAKVTGDEWGDNYFLV 65
            |||.|:||::||.||:||::|||.|:|||||:||||||||||||||:||||::|.:|||:|||||
Zfish     1 MPLARSLSVTSLSGLDDWDEEFDREDAVLFEIAWEVANKVGGIYTVIQTKARLTCEEWGENYFLV 65

Human    66 GPYTEQGVRTQVELLEAPTPALKRTLDSMNSKGCKVYFGRWLIEGGPLVVLLDVGASAWALERWK 130
            |||.|..|||||||:|....||:||:|.|||.|||||||||||||.|.|||||||.:||:|:|||
Zfish    66 GPYMESNVRTQVELIEPCNAALRRTIDKMNSSGCKVYFGRWLIEGSPYVVLLDVGFTAWSLDRWK 130

Human   131 GELWDTCNIGVPWYDREANDAVLFGFLTTWFLGEFLAQSEEKPHVVAHFHEWLAGVGLCLCRARR 195
            .|||:.|||||||:||||||||||||||.|.|||:.||.:|.||:||||||||||:||.|||.|:
Zfish   131 SELWEKCNIGVPWFDREANDAVLFGFLTAWLLGEYAAQCDEPPHIVAHFHEWLAGLGLVLCRQRQ 195

Human   196 LPVATIFTTHATLLGRYLCAGAVDFYNNLENFNVDKEAGERQIYHRYCMERAAAHCAHVFTTVSQ 260
            |||:|||||||||||||||||.|||||||..||||||||:||||||||:||||..||||||||||
Zfish   196 LPVSTIFTTHATLLGRYLCAGNVDFYNNLAEFNVDKEAGDRQIYHRYCLERAACRCAHVFTTVSQ 260

Human   261 ITAIEAQHLLKRKPDIVTPNGLNVKKFSAMHEFQNLHAQSKARIQEFVRGHFYGHLDFNLDKTLY 325
            ||||||:||||||||||||||||||||||||||||||||||||||||||||||||||||||||::
Zfish   261 ITAIEAEHLLKRKPDIVTPNGLNVKKFSAMHEFQNLHAQSKARIQEFVRGHFYGHLDFNLDKTVF 325

Human   326 FFIAGRYEFSNKGADVFLEALARLNYLLRVNGSEQTVVAFFIMPARTNNFNVETLKGQAVRKQLW 390
            .||||||||||||||:|||||||||||||||.||.||:|||||||||||||||||||||||||||
Zfish   326 LFIAGRYEFSNKGADIFLEALARLNYLLRVNHSEVTVIAFFIMPARTNNFNVETLKGQAVRKQLW 390

Human   391 DTANTVKEKFGRKLYESLLVGSLPDMNKMLDKEDFTMMKRAIFATQRQSFPPVCTHNMLDDSSDP 455
            |||.:|||:||:|||||||||.|||::|||||||||||||||||||||..|||||||||:|||||
Zfish   391 DTAQSVKERFGKKLYESLLVGQLPDVSKMLDKEDFTMMKRAIFATQRQCQPPVCTHNMLEDSSDP 455

Human   456 ILTTIRRIGLFNSSADRVKVIFHPEFLSSTSPLLPVDYEEFVRGCHLGVFPSYYEPWGYTPAECT 520
            ||..|||||||||:.||||||||||||||||||||:|||||||||||||||||||||||||||||
Zfish   456 ILNCIRRIGLFNSAQDRVKVIFHPEFLSSTSPLLPMDYEEFVRGCHLGVFPSYYEPWGYTPAECT 520

Human   521 VMGIPSISTNLSGFGCFMEEHIADPSAYGIYILDRRFRSLDDSCSQLTSFLYSFCQQSRRQRIIQ 585
            ||||||||||||||||||||||||||||||||||||:||:|:||:||||||:.||||||||||||
Zfish   521 VMGIPSISTNLSGFGCFMEEHIADPSAYGIYILDRRYRSVDESCNQLTSFLFQFCQQSRRQRIIQ 585

Human   586 RNRTERLSDLLDWKYLGRYYMSARHMALSKAFPEHFTYEPNEADAAQGYRYPRPASVPPSPSLSR 650
            |||||||||||||:||||||:||||:||:||:|:.:.|||.|..:|.|:||||||||||||:.|.
Zfish   586 RNRTERLSDLLDWRYLGRYYVSARHLALAKAYPDTYIYEPQEPSSAAGFRYPRPASVPPSPAHSL 650

Human   651 HSSPHQS--EDEEDPRNGPLEEDGERYDEDEEAAKDRRNIRAP 691
            |||||.|  ||||:|           ||||.||.|||.|||.|
Zfish   651 HSSPHHSEAEDEEEP-----------YDEDLEAEKDRVNIRQP 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GYS1	NP_002094.2	Glycogen_syn	31..663	CDD:399009	534/633 (84%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	634..737		37/60 (62%)
gys1	NP_957474.1	GT3_GSY2-like	26..615	CDD:340824	506/588 (86%)