Protein Alignment GYS1 and gys1

DIOPT Version :10

• Sequence 1: NP_002094.2
• Gene: GYS1 / 2997
• HGNCID: 4706
• Length: 737
• Species: Homo sapiens
• Sequence 2: XP_002939278.3
• Gene: gys1 / 100490155
• XenbaseID: XB-GENE-974345
• Length: 736
• Species: Xenopus tropicalis
• Alignment Length: 746
• Identity: 606/746 - (81%)
• Similarity: 671/746 - (89%)
• Gaps: 19/746 - (2%)

Human     1 MPLNRTLSMSSLPGLEDWEDEFDLENAVLFEVAWEVANKVGGIYTVLQTKAKVTGDEWGDNYFLV 65
            |||.|:||::||.|||||:|:.||||::||||||||||||||||||:|||||||.||||:||||:
 Frog     1 MPLARSLSVTSLTGLEDWDDDLDLENSILFEVAWEVANKVGGIYTVIQTKAKVTTDEWGENYFLI 65

Human    66 GPYTEQGVRTQVELLEAPTPALKRTLDSMNSKGCKVYFGRWLIEGGPLVVLLDVGASAWALERWK 130
            |||.|..|||||||:|...||:||.|||||:||||||||||||||.|.|:|:|:.|:||.|:|||
 Frog    66 GPYFENNVRTQVELIEPTHPAIKRALDSMNAKGCKVYFGRWLIEGSPYVILIDIAATAWNLDRWK 130

Human   131 GELWDTCNIGVPWYDREANDAVLFGFLTTWFLGEFLAQSEEKPHVVAHFHEWLAGVGLCLCRARR 195
            .||||:|:||:|||||||||||||||||.||||||.||.||||.::||||||||||||||||.|:
 Frog   131 TELWDSCDIGIPWYDREANDAVLFGFLTAWFLGEFSAQCEEKPFIIAHFHEWLAGVGLCLCRIRK 195

Human   196 LPVATIFTTHATLLGRYLCAGAVDFYNNLENFNVDKEAGERQIYHRYCMERAAAHCAHVFTTVSQ 260
            |||||||||||||||||||||.|||||||::||||||||:|||||||||||||..|:||||||||
 Frog   196 LPVATIFTTHATLLGRYLCAGNVDFYNNLQSFNVDKEAGDRQIYHRYCMERAAVQCSHVFTTVSQ 260

Human   261 ITAIEAQHLLKRKPDIVTPNGLNVKKFSAMHEFQNLHAQSKARIQEFVRGHFYGHLDFNLDKTLY 325
            ||||||:||||||||||||||||||||||||||||||||||.|||||:||||||||||||||||:
 Frog   261 ITAIEAEHLLKRKPDIVTPNGLNVKKFSAMHEFQNLHAQSKGRIQEFIRGHFYGHLDFNLDKTLF 325

Human   326 FFIAGRYEFSNKGADVFLEALARLNYLLRVNGSEQTVVAFFIMPARTNNFNVETLKGQAVRKQLW 390
            |||||||||||||||||||||||||||||||.||.|:|||||||||||||||||||||||||||.
 Frog   326 FFIAGRYEFSNKGADVFLEALARLNYLLRVNHSETTIVAFFIMPARTNNFNVETLKGQAVRKQLC 390

Human   391 DTANTVKEKFGRKLYESLLVGSLPDMNKMLDKEDFTMMKRAIFATQRQSFPPVCTHNMLDDSSDP 455
            |||||:|||||:|||||||||:|||||||||||||||:|||||||||.||||:|||||||||:|.
 Frog   391 DTANTIKEKFGKKLYESLLVGNLPDMNKMLDKEDFTMLKRAIFATQRHSFPPICTHNMLDDSTDA 455

Human   456 ILTTIRRIGLFNSSADRVKVIFHPEFLSSTSPLLPVDYEEFVRGCHLGVFPSYYEPWGYTPAECT 520
            ||.|||||||||||:||||||||||||||||||||:|||||||||||||||||||||||||||||
 Frog   456 ILNTIRRIGLFNSSSDRVKVIFHPEFLSSTSPLLPMDYEEFVRGCHLGVFPSYYEPWGYTPAECT 520

Human   521 VMGIPSISTNLSGFGCFMEEHIADPSAYGIYILDRRFRSLDDSCSQLTSFLYSFCQQSRRQRIIQ 585
            ||||||:||||||||||||||||||:||||||.||||||:|:||:|||||||||.||:|||||||
 Frog   521 VMGIPSVSTNLSGFGCFMEEHIADPTAYGIYIQDRRFRSVDESCTQLTSFLYSFSQQTRRQRIIQ 585

Human   586 RNRTERLSDLLDWKYLGRYYMSARHMALSKAFPEHFTYEPNEADAAQGYRYPRPASVPPSPSLSR 650
            ||||||||||||||||||||..||||||:||||::|||||:|..||||:||||||||||||||||
 Frog   586 RNRTERLSDLLDWKYLGRYYTYARHMALAKAFPDNFTYEPHEPTAAQGFRYPRPASVPPSPSLSR 650

Human   651 HSSPHQSEDEEDPRNGPLEEDGERYDEDEEAAKDRRNIR---------APEWPRRASCTSSTSGS 706
            |||||.||.|:|          |||||:|||.|||:||:         ||||.||:...|..:.:
 Frog   651 HSSPHHSETEDD----------ERYDEEEEAEKDRQNIKQPSITSMASAPEWRRRSKKGSIDATN 705

Human   707 KRNSVDTATSSSLSTPSEPLSPTSSLGEERN 737
            ..|:.:.:|.::.|:||:..||||||.||||
 Frog   706 SSNASNASTPTNPSSPSDLSSPTSSLIEERN 736

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GYS1	NP_002094.2	Glycogen_syn	31..663	CDD:399009	550/631 (87%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	634..737		58/111 (52%)
gys1	XP_002939278.3	GT3_GSY2-like	26..615	CDD:340824	515/588 (88%)