Protein Alignment CERS2 and schlank

DIOPT Version :10

• Sequence 1: XP_011507753.1
• Gene: CERS2 / 29956
• HGNCID: 14076
• Length: 400
• Species: Homo sapiens
• Sequence 2: NP_652526.1
• Gene: schlank / 50392
• FlyBaseID: FBgn0040918
• Length: 400
• Species: Drosophila melanogaster
• Alignment Length: 367
• Identity: 146/367 - (39%)
• Similarity: 216/367 - (58%)
• Gaps: 6/367 - (1%)

Human    21 MLQTLYDYFWWERLWLPVNLTWADLE--DRDGRVYAKASDLYITLPLALLFLIVRYFFELYVATP 83
            :|....:.||...:|||.|.||||:.  .|...|:|...||...:|.|.:.::|||..|.:..:|
  Fly     3 ILNEFSNVFWSTHIWLPPNTTWADIAPGSRPDVVHANYKDLIWPIPFAAVVMLVRYTLERFWISP 67

Human    84 LAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDRPS 148
            :...|.|:.....:|.....||..|..|.:..|:..|. ||:|:.:|.|::|||:|.||.||:||
  Fly    68 VGKSLGIRSSRPKKAANVPILEKTYAKSTRLDKKKLVP-LSKQTDMSEREIERWWRLRRAQDKPS 131

Human   149 LLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQYWYYMIELSFYWSL 213
            .|.||.|.:||..:||.:||.|:.|:.|||||:|:|..|.|||.||.....:|||||.:||||||
  Fly   132 TLVKFCENTWRCIYYLYSFIFGVIVLWDKPWFWDVKSCWYGYPHQSISNDIWWYYMISMSFYWSL 196

Human   214 LFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHDSSDYLLESAKMFNYAGWK 278
            ..:...|||||||.:..|||:.|::|:|.||..|..|.|:|::.:||.:|..||:||:..||.::
  Fly   197 TGTQFFDVKRKDFWQMFIHHMVTLLLMSLSWVCNLHRVGSLVLVVHDCADIFLEAAKLTKYAKYQ 261

Human   279 NTCNNIFIVFAIVFIITRLVILPFWILHCTLVYPLELYPAFFGYYFFNSMMGVLQLLHIFWAYLI 343
            ..|:.||.:|.:|:|:|||...| .|::.:.|....:.|.|..||.|||::.:|.:||:.|.|:|
  Fly   262 KLCDAIFAIFTVVWIVTRLGFYP-RIIYSSSVEAPRILPMFPAYYIFNSLLLMLLVLHVIWTYMI 325

Human   344 LRMAHKFITGKLVEDE--RSDREETESSEGEEAAAGGGAKSR 383
            |::....:...|:..:  .||.|:...|.|......|.|:|:
  Fly   326 LKIVVDSLQKGLMSGDIRSSDSEDLTDSSGNARLTNGSARSK 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CERS2	XP_011507753.1	homeodomain	91..148	CDD:238039	20/56 (36%)
		TLC	151..352	CDD:214789	89/200 (45%)
schlank	NP_652526.1	homeodomain	75..131	CDD:238039	20/56 (36%)
		TLC	135..334	CDD:214789	89/199 (45%)