Protein Alignment Myo1a and zip

DIOPT Version :9

• Sequence 1: NP_062197.1
• Gene: Myo1a / 299509
• RGDID: 3135
• Length: 1043
• Species: Rattus norvegicus
• Sequence 2: NP_523860.2
• Gene: zip / 38001
• FlyBaseID: FBgn0265434
• Length: 2056
• Species: Drosophila melanogaster
• Alignment Length: 916
• Identity: 301/916 - (32%)
• Similarity: 460/916 - (50%)
• Gaps: 174/916 - (18%)

  Rat    10 VEDLILLEPLDEESLIKNLQLRYEKKEIYTYIGNVVISMNPYQQLPIYGPEFIAKYRDYTFYELK 74
            |||:..|..|:|.|::.|::.||....||||.|...:.:|||::||||..:.:.:|:....:|:.
  Fly   133 VEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPYKKLPIYTEKIMERYKGIKRHEVP 197

  Rat    75 PHIYALANVAYQSLKDRDRDQCILITGESGAGKTEASKLV---MSYVAAVCGKG----------- 125
            ||::|:.:.||:::.....||.||.||||||||||.:|.|   ::||||...||
  Fly   198 PHVFAITDSAYRNMLGDREDQSILCTGESGAGKTENTKKVIQFLAYVAASKPKGSGAVPHPAVLI 262

  Rat   126 -----------------------EQVNSVK--------------EQLLQSNPVLEAFGNAKTIRN 153
                                   |.||.:|              :||||:||:|||||||||::|
  Fly   263 NFSVNTNKYIKVKIMAQNQNQTIEVVNGLKMVEVNSNCQEGELEQQLLQANPILEAFGNAKTVKN 327

  Rat   154 DNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKSRVVKQLKGERNFHIFYQLLAGADTQLLKALKL 218
            ||||||||::.|.||..|...|..|..|||||||.::|.|.||.|||||||||||..:..:...|
  Fly   328 DNSSRFGKFIRINFDASGFISGANIETYLLEKSRAIRQAKDERTFHIFYQLLAGATPEQREKFIL 392

  Rat   219 EEDARGYAYLNGEVSRVNGMDDASNFRAVQNAMAVIGFSEEEIRQVLEVTALVLKLGNVKLADE- 282
             :|.:.||:|:.....|.|:||.:.|:|...:|.::|.:.|:...:..:.:.||..|::|...|
  Fly   393 -DDVKSYAFLSNGSLPVPGVDDYAEFQATVKSMNIMGMTSEDFNSIFRIVSAVLLFGSMKFRQER 456

  Rat   283 --FQANGLPASGVCDGKGIQEIGEMMGLNSAELEKALCSRTMETGKEKVVTVLNVIQAQYARDAL 345
              .||. ||     |....|:|..::||:..::.:|..:..::.|::.|.......|.::|.:|:
  Fly   457 NNDQAT-LP-----DNTVAQKIAHLLGLSVTDMTRAFLTPRIKVGRDFVTKAQTKEQVEFAVEAI 515

  Rat   346 AKNIYSRLFDWIVNRINESIKVGTGEKRKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIE 410
            ||..|.|:|.|:|||||.|:.....:....:|:||:.||||.|.|||||..|||.||||||:|..
  Fly   516 AKACYERMFKWLVNRINRSLDRTKRQGASFIGILDMAGFEIFELNSFEQLCINYTNEKLQQLFNH 580

  Rat   411 LTLKEEQEEYKREGIPWTKVEYFDNGI----ICDLIEHSQRGILAMLDEECLRPGVVSDTTFLAK 471
            .....|||||:||||.|   ::.|.|:    ..|||: ...||:|:|||||..| ..:|.||:.|
  Fly   581 TMFILEQEEYQREGIEW---KFIDFGLDLQPTIDLID-KPGGIMALLDEECWFP-KATDKTFVDK 640

  Rat   472 LNQLFSKHSHYESKVTQNAQRQYDRT--MGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLSQT 534
            |....|.|.            ::.:|  .|::.|.|.||||:|.|:...::.||.|.|..::...
  Fly   641 LVSAHSMHP------------KFMKTDFRGVADFAIVHYAGRVDYSAAKWLMKNMDPLNENIVSL 693

  Rat   535 MWKAQHPLLHSLFPEGNPKEASLKRPPTAGTQF----------------KNSVAILMKNLYSKNP 583
            :..:|.|.:.:::.:.  :...:.:.....|||                |..:|.||..|.:.||
  Fly   694 LQGSQDPFVVNIWKDA--EIVGMAQQALTDTQFGARTRKGMFRTVSHLYKEQLAKLMDTLRNTNP 756

  Rat   584 NYIRCIKPNDQQQQGRFTSELVMVQARYLGLLENVRVRRAGYAFRQAYKPFLERYRLLSRSTWPR 648
            |::|||.||.:::.|:..:.||:.|.|..|:||.:|:.|.|:..|..::.|.:||.||:.:..|:
  Fly   757 NFVRCIIPNHEKRAGKIDAPLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYELLTPNVIPK 821

  Rat   649 WNGEDREGVEKVLGSLILSSEELAYGRTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKVYRGWRC 713
            ...:.::..||::.:|.|.|.....|::|||.|: ..|.:|||:|..::..|
  Fly   822 GFMDGKKACEKMIQALELDSNLYRVGQSKIFFRA-GVLAHLEEERDFKISDL------------- 872

  Rat   714 RTHYQQMRKSQILISAWFRGNKQKKHYGKIRSSVLLIQAFVRGWKARKNYRKYFRSGAAITLANF 778
                                             ::..|||.||:.||:||:|..:...||.:
  Fly   873 ---------------------------------IVNFQAFCRGFLARRNYQKRLQQLNAIRI--- 901

  Rat   779 IYQSITQKFLLNLKKNLPSTKVLDN-TWPAAPYRCFNTANQELQHLFYQWKCKKYRDQLSPKQVQ 842
                        :::|..:...|.| .|    :|.:......|:....:.|..:..|:|  |||
  Fly   902 ------------IQRNCAAYLKLRNWQW----WRLYTKVKPLLEVTKQEEKLVQKEDEL--KQV- 947

  Rat   843 TLREKL 848
              ||||
  Fly   948 --REKL 951

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo1a	NP_062197.1	MYSc_Myo1	22..681	CDD:276829	260/734 (35%)
		IQ	742..764	CDD:197470	8/21 (38%)
		Myosin_TH1	847..1042	CDD:399188	2/2 (100%)
zip	NP_523860.2	Myosin_N	80..117	CDD:280832
		Myosin_head	133..854	CDD:278492	266/746 (36%)
		MYSc_Myh2_insects_mollusks	145..854	CDD:276876	260/734 (35%)
		Myosin_tail_1	931..2011	CDD:279860	10/26 (38%)
		Prefoldin	1431..1515	CDD:298833
		FAM76	<1847..1926	CDD:292665

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000