Protein Alignment RPA4 and RPA2

DIOPT Version :10

• Sequence 1: NP_037479.1
• Gene: RPA4 / 29935
• HGNCID: 30305
• Length: 261
• Species: Homo sapiens
• Sequence 2: NP_610077.1
• Gene: RPA2 / 35364
• FlyBaseID: FBgn0288834
• Length: 246
• Species: Drosophila melanogaster
• Alignment Length: 257
• Identity: 63/257 - (24%)
• Similarity: 113/257 - (43%)
• Gaps: 25/257 - (9%)

Human     8 SYGSISAADGASGGSDQLCERDATPAIKTQRPKVRIQDVVPCNVNQLLSSTVFDPVFKVRGIIVS 72
            |:|..:|...|..|           |...|:.    :.:||..|.|::.:.  :...::.|:..:
  Fly     4 SFGDFNATQTAPTG-----------AASNQKG----EGIVPLVVKQIVDAP--EGNIELFGMQYA 51

Human    73 QVSIVGVIRGAEKASNHICYKIDDMTAKPIEARQWFGREKVKQVTPLSVGVYVKVFGILKCPTGT 137
            ...:|.::|..|.:|..|.|.::|.:.: |:|..|.......:...:.|..||||:|..:...|:
  Fly    52 MACVVAIVRNVETSSTKITYTLEDHSGR-IDAHYWLEEGDALKAPEVMVNNYVKVYGTTRSQGGS 115

Human   138 KSLEVLKIHVLEDMNEFTVHILETVNAHMMLDKARRDTTVESVPVSPSEVNDAGDNDESHRNFI- 201
            |:|.:.|:..:.|.||...|:||.:||....:..:......:...:.|......|...|..:.|
  Fly   116 KTLMIFKLLPVLDPNEVCTHLLEVLNARYRAEDYQSKGGAGAGAGASSGSGSIADFTASQSSAIV 180

Human   202 ------QDEVLRLIHECPHQEGKSIHELRAQLCDLSVKAIKEAIDYLTVEGHIYPTVDREHF 257
                  |..|.:.|.....:||.|..||:|:...:|...:...:|::..|||||.::|.:||
  Fly   181 SGLEPKQQAVFQAIKSNVSEEGISRKELKAKFSHISDSELTNILDFMISEGHIYSSIDADHF 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RPA4	NP_037479.1	RFA2	32..259	CDD:227560	58/233 (25%)
		RPA2_DBD_D	73..166	CDD:239924	28/92 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	175..194		2/18 (11%)
RPA2	NP_610077.1	RFA2	12..246	CDD:227560	60/249 (24%)
		RPA2_DBD_D	52..144	CDD:239924	28/92 (30%)