Protein Alignment GUSB and gusb

DIOPT Version :10

• Sequence 1: NP_000172.2
• Gene: GUSB / 2990
• HGNCID: 4696
• Length: 651
• Species: Homo sapiens
• Sequence 2: XP_009299404.1
• Gene: gusb / 571441
• ZFINID: ZDB-GENE-070705-256
• Length: 644
• Species: Danio rerio
• Alignment Length: 652
• Identity: 424/652 - (65%)
• Similarity: 521/652 - (79%)
• Gaps: 31/652 - (4%)

Human     4 GSAVAWAALGPLLWGCAL---------GLQGGMLYPQESPSRECKELDGLWSFRADFSDNRRRGF 59
            |||.|..|:     .|||         .||||||:|::|||||.|::.||||||||.||||.|||
Zfish     3 GSAAARLAV-----KCALLAAICSRCRALQGGMLFPRDSPSREVKDVSGLWSFRADLSDNRNRGF 62

Human    60 EEQWYRRPLWESGPTVDMPVPSSFNDISQDWRLRHFVGWVWYEREVILPERWTQDLRTRVVLRIG 124
            ||||:.|||.|:||.:|||||||:|||:||.::|.||||||||:||::|.||.||..||:|||:|
Zfish    63 EEQWFSRPLEETGPVIDMPVPSSYNDITQDAKIRDFVGWVWYEKEVLVPTRWIQDRGTRIVLRVG 127

Human   125 SAHSYAIVWVNGVDTLEHEGGYLPFEADISNLVQV---GPLPSRLRITIAINNTLTPTTLPPGTI 186
            |||.|:::|||||...||.||:||||||||::::.   ||    .|||||:||||:..|||||||
Zfish   128 SAHYYSVLWVNGVQMTEHAGGHLPFEADISSVLRQSSGGP----CRITIAVNNTLSLETLPPGTI 188

Human   187 QYLTDTSKYPKGYFVQNTYFDFFNYAGLQRSVLLYTTPTTYIDDITVTTSVEQDSGLVNYQISVK 251
            ||:.|.::||.|||||||.||||||||:.|||||||||..:||||||.|:...:.|||:|.:||.
Zfish   189 QYMNDRTRYPSGYFVQNTNFDFFNYAGIHRSVLLYTTPAVHIDDITVQTTFSDNIGLVSYNVSVL 253

Human   252 GSNLFKLEVRLLDAENKVVANGTGTQGQLKVPGVSLWWPYLMHERPAYLYSLEVQLTAQTSLGPV 316
            |.:...::|.|...:.:.||:..|..|.||:..|:|||||||||.|.||||:|||..|:..   .
Zfish   254 GGSKAAVKVTLSAKDGRCVASSEGLSGVLKITDVNLWWPYLMHENPGYLYSMEVQAIAEDG---Q 315

Human   317 SDFYTLPVGIRTVAVTKSQFLINGKPFYFHGVNKHEDADIRGKGFDWPLLVKDFNLLRWLGANAF 381
            :|.||||||:|||.||:|:||||.|.|||||||||||||||||||||||:||||||::|:|||:|
Zfish   316 TDIYTLPVGVRTVQVTRSKFLINNKLFYFHGVNKHEDADIRGKGFDWPLVVKDFNLMKWMGANSF 380

Human   382 RTSHYPYAEEVMQMCDRYGIVVIDECPGVGLALPQFFNNVSLHHHMQVMEEVVRRDKNHPAVVMW 446
            ||||||||||::|..||:|||:||||||||:...:.|.||||.||:.||||:||||||||:||||
Zfish   381 RTSHYPYAEEILQTADRHGIVIIDECPGVGIKDIRSFGNVSLAHHLTVMEELVRRDKNHPSVVMW 445

Human   447 SVANEPASHLESAGYYLKMVIAHTKSLDPSRPVTFVSNSNYAADKGAPYVDVICLNSYYSWYHDY 511
            ||||||||.:..||.|.|.:|:||||||.||||||:::||||.|:|||||||:|:|||:|||||.
Zfish   446 SVANEPASEMPPAGLYFKELISHTKSLDSSRPVTFITDSNYARDQGAPYVDVVCVNSYFSWYHDP 510

Human   512 GHLELIQLQLATQFENWYKKYQKPIIQSEYGAETIAGFHQDPPLMFTEEYQKSLLEQYHLGLDQK 576
            ||.|||:|||:|||:||:.|||||||||||||:.:.|.|.|||:|||||||:::|:.||...|||
Zfish   511 GHTELIRLQLSTQFDNWHGKYQKPIIQSEYGADAVPGLHSDPPMMFTEEYQRAVLQNYHSVFDQK 575

Human   577 RRKYVVGELIWNFADFMTEQSPTRVLGNKKGIFTRQRQPKSAAFLLRERYWKIANE-------TR 634
            |:::|:||||||||||||.|:.|||:|||||:||||||||:.||:||||||:||||       :|
Zfish   576 RKEFVIGELIWNFADFMTAQTITRVVGNKKGVFTRQRQPKAGAFILRERYWRIANESGVLPTWSR 640

Human   635 YP 636
            ||
Zfish   641 YP 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GUSB	NP_000172.2	Bgal_small_N	27..631	CDD:481240	406/606 (67%)
gusb	XP_009299404.1	Bgal_small_N	30..630	CDD:481240	406/606 (67%)