Protein Alignment GUSB and Gusb

DIOPT Version :10

• Sequence 1: NP_000172.2
• Gene: GUSB / 2990
• HGNCID: 4696
• Length: 651
• Species: Homo sapiens
• Sequence 2: NP_034498.1
• Gene: Gusb / 110006
• MGIID: 95872
• Length: 648
• Species: Mus musculus
• Alignment Length: 646
• Identity: 484/646 - (74%)
• Similarity: 552/646 - (85%)
• Gaps: 4/646 - (0%)

Human     6 AVAWAALGPLLWGCALGLQGGMLYPQESPSRECKELDGLWSFRADFSDNRRRGFEEQWYRRPLWE 70
            :..|.|||.||..|||.|:||||:|:||||||.|.|||||.||||.|:||.:|||:||||:||.|
Mouse     6 SACWVALGQLLCSCALALKGGMLFPKESPSRELKALDGLWHFRADLSNNRLQGFEQQWYRQPLRE 70

Human    71 SGPTVDMPVPSSFNDISQDWRLRHFVGWVWYEREVILPERWTQDLRTRVVLRIGSAHSYAIVWVN 135
            |||.:|||||||||||:|:..||.|:||||||||.|||.|||||...||||||.|||.||:||||
Mouse    71 SGPVLDMPVPSSFNDITQEAALRDFIGWVWYEREAILPRRWTQDTDMRVVLRINSAHYYAVVWVN 135

Human   136 GVDTLEHEGGYLPFEADISNLVQVGPLPSRLRITIAINNTLTPTTLPPGTIQYLTDTSKYPKGYF 200
            |:..:|||||:||||||||.|||.||| :..||||||||||||.|||||||.|.||||.||||||
Mouse   136 GIHVVEHEGGHLPFEADISKLVQSGPL-TTCRITIAINNTLTPHTLPPGTIVYKTDTSMYPKGYF 199

Human   201 VQNTYFDFFNYAGLQRSVLLYTTPTTYIDDITVTTSVEQDSGLVNYQISVKGSNLFKLEVRLLDA 265
            ||:|.|||||||||.|||:||||||||||||||.|:||||.|||.|.|||:||..|:|||:|||.
Mouse   200 VQDTSFDFFNYAGLHRSVVLYTTPTTYIDDITVITNVEQDIGLVTYWISVQGSEHFQLEVQLLDE 264

Human   266 ENKVVANGTGTQGQLKVPGVSLWWPYLMHERPAYLYSLEVQLTAQTSLGPVSDFYTLPVGIRTVA 330
            ..||||:|||.||||:||..:|||||||||.|||:|||||::|...|   |:|:||||:||||||
Mouse   265 GGKVVAHGTGNQGQLQVPSANLWWPYLMHEHPAYMYSLEVKVTTTES---VTDYYTLPIGIRTVA 326

Human   331 VTKSQFLINGKPFYFHGVNKHEDADIRGKGFDWPLLVKDFNLLRWLGANAFRTSHYPYAEEVMQM 395
            ||||:||||||||||.|||||||:|||||||||||||||||||||||||:||||||||:|||:|:
Mouse   327 VTKSKFLINGKPFYFQGVNKHEDSDIRGKGFDWPLLVKDFNLLRWLGANSFRTSHYPYSEEVLQL 391

Human   396 CDRYGIVVIDECPGVGLALPQFFNNVSLHHHMQVMEEVVRRDKNHPAVVMWSVANEPASHLESAG 460
            ||||||||||||||||:.|||.|.|.||.||::||||:|||||||||||||||||||:|.|:.|.
Mouse   392 CDRYGIVVIDECPGVGIVLPQSFGNESLRHHLEVMEELVRRDKNHPAVVMWSVANEPSSALKPAA 456

Human   461 YYLKMVIAHTKSLDPSRPVTFVSNSNYAADKGAPYVDVICLNSYYSWYHDYGHLELIQLQLATQF 525
            ||.|.:|.|||:||.:||||||||:.|.||.|||||||||:|||:||||||||||:||.||.:||
Mouse   457 YYFKTLITHTKALDLTRPVTFVSNAKYDADLGAPYVDVICVNSYFSWYHDYGHLEVIQPQLNSQF 521

Human   526 ENWYKKYQKPIIQSEYGAETIAGFHQDPPLMFTEEYQKSLLEQYHLGLDQKRRKYVVGELIWNFA 590
            |||||.:|||||||||||:.|.|.|:|||.||:|||||::||.||..|||||::|||||||||||
Mouse   522 ENWYKTHQKPIIQSEYGADAIPGIHEDPPRMFSEEYQKAVLENYHSVLDQKRKEYVVGELIWNFA 586

Human   591 DFMTEQSPTRVLGNKKGIFTRQRQPKSAAFLLRERYWKIANETRYPHSVAKSQCLENSLFT 651
            ||||.|||.||:||||||||||||||::||:||||||:|||||....|..::||..:..||
Mouse   587 DFMTNQSPLRVIGNKKGIFTRQRQPKTSAFILRERYWRIANETGGHGSGPRTQCFGSRPFT 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GUSB	NP_000172.2	Bgal_small_N	27..631	CDD:481240	463/603 (77%)
Gusb	NP_034498.1	Bgal_small_N	27..627	CDD:481240	463/603 (77%)