Protein Alignment GUSB and gusb

DIOPT Version :10

• Sequence 1: NP_000172.2
• Gene: GUSB / 2990
• HGNCID: 4696
• Length: 651
• Species: Homo sapiens
• Sequence 2: XP_002935849.2
• Gene: gusb / 100101670
• XenbaseID: XB-GENE-921780
• Length: 633
• Species: Xenopus tropicalis
• Alignment Length: 629
• Identity: 417/629 - (66%)
• Similarity: 505/629 - (80%)
• Gaps: 11/629 - (1%)

Human     9 WAALGPLLWGC-ALGLQGGMLYPQESPSRECKELDGLWSFRADFSDNRRRGFEEQWYRRPLWESG 72
            |..|  ||..| |..|.||:|||:|:|:||.|||.|:||||||.|..|.:||:||||:|||.|:|
 Frog     8 WLFL--LLHSCLAYTLNGGILYPRETPTRELKELSGIWSFRADKSPQRDKGFQEQWYKRPLGETG 70

Human    73 PTVDMPVPSSFNDISQDWRLRHFVGWVWYEREVILPERWTQ-DLRTRVVLRIGSAHSYAIVWVNG 136
            |.:|||||:|:|||:||..||.|:||||||:|:.||.:|.: ...:||:|||||||.::::||||
 Frog    71 PVIDMPVPASYNDITQDISLRDFIGWVWYEKEIWLPSQWVEKTASSRVMLRIGSAHYFSVIWVNG 135

Human   137 VDTLEHEGGYLPFEADISNLVQ--VGPLPSRLRITIAINNTLTPTTLPPGTIQYLTDTSKYPKGY 199
            :..:|||||:||||.:|||:::  .|.|   .|||||:|||||..||||||||::.|:::|||||
 Frog   136 IQVMEHEGGHLPFETEISNILKDSAGSL---CRITIAVNNTLTLHTLPPGTIQFMEDSTRYPKGY 197

Human   200 FVQNTYFDFFNYAGLQRSVLLYTTPTTYIDDITVTTSVEQDSGLVNYQISVKGSNLFKLEVRLLD 264
            ||||..||||||||:.|.|:|||||:.|||||||....:.::|::||.:||.||..:.:.|.|.|
 Frog   198 FVQNIEFDFFNYAGIHRPVVLYTTPSIYIDDITVIMDTDGNTGIINYVVSVVGSESYSVSVTLRD 262

Human   265 AENKVVANGTGTQGQLKVPGVSLWWPYLMHERPAYLYSLEVQLTAQTSLGPVSDFYTLPVGIRTV 329
            .:.:|.|:|....|.|.||...|||||||||.|.|||||||.|.|:...|.|.|.|.||||||||
 Frog   263 RQGQVAAHGVEAIGHLVVPDAKLWWPYLMHEEPGYLYSLEVMLLAKNGNGSVEDNYILPVGIRTV 327

Human   330 AVTKSQFLINGKPFYFHGVNKHEDADIRGKGFDWPLLVKDFNLLRWLGANAFRTSHYPYAEEVMQ 394
            .|:..|||||||||||||||||||.|:||||.||.|:|||||||:|||||:|||||||||||:|.
 Frog   328 HVSGDQFLINGKPFYFHGVNKHEDYDVRGKGLDWSLIVKDFNLLKWLGANSFRTSHYPYAEEIMD 392

Human   395 MCDRYGIVVIDECPGVGLALPQFFNNVSLHHHMQVMEEVVRRDKNHPAVVMWSVANEPASHLESA 459
            :||:|||||||||||||:..|:.|.|.||:||:.||||:||||||.|:||||||||||||.|..|
 Frog   393 LCDKYGIVVIDECPGVGIKYPESFGNQSLNHHLIVMEELVRRDKNRPSVVMWSVANEPASQLPVA 457

Human   460 GYYLKMVIAHTKSLDPSRPVTFVSNSNYAADKGAPYVDVICLNSYYSWYHDYGHLELIQLQLATQ 524
            |||.|.||.:||.|||:||||:|||:||..|:|||||||||:|||:|||||.||||:|||||..|
 Frog   458 GYYFKTVIGYTKQLDPTRPVTYVSNANYEHDQGAPYVDVICVNSYFSWYHDAGHLEVIQLQLNDQ 522

Human   525 FENWYKKYQKPIIQSEYGAETIAGFHQDPPLMFTEEYQKSLLEQYHLGLDQKRRKYVVGELIWNF 589
            |:.||:|||||:|||||||:||.|||.|||||||||||:.:||.||...|||  |:|:|||||||
 Frog   523 FDKWYEKYQKPMIQSEYGADTIPGFHSDPPLMFTEEYQRVVLENYHTVFDQK--KFVIGELIWNF 585

Human   590 ADFMTEQSPTRVLGNKKGIFTRQRQPKSAAFLLRERYWKIANET 633
            |||||.||.|||:|||||||||||||||:|::||:||.|:||.|
 Frog   586 ADFMTAQSVTRVVGNKKGIFTRQRQPKSSAYILRDRYLKLANAT 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GUSB	NP_000172.2	Bgal_small_N	27..631	CDD:481240	405/606 (67%)
gusb	XP_002935849.2	Bgal_small_N	26..633	CDD:481240	408/609 (67%)