Protein Alignment CNOT7 and POP2

DIOPT Version :10

• Sequence 1: NP_001309022.1
• Gene: CNOT7 / 29883
• HGNCID: 14101
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_014450.3
• Gene: POP2 / 855788
• SGDID: S000005335
• Length: 433
• Species: Saccharomyces cerevisiae
• Alignment Length: 290
• Identity: 104/290 - (35%)
• Similarity: 157/290 - (54%)
• Gaps: 41/290 - (14%)

Human    14 EVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADYQYQLLRCNVDLLKIIQLG 78
            :||..||..|...|||::.:||:|::.|||.|.:|||||.|||..||.||.:|.|||.|..||||
Yeast   162 DVWKSNLYSEFAVIRQLVSQYNHVSISTEFVGTLARPIGTFRSKVDYHYQTMRANVDFLNPIQLG 226

Human    79 LTFMNEQGEYPP-GTSTWQFNFKFNLTLGVVAHACNPSTLGGRGGRITREDMYAQDSIELLTTSG 142
            |:..:..|..|. |.|||||||:|:                      .::::.:.:|:|||..||
Yeast   227 LSLSDANGNKPDNGPSTWQFNFEFD----------------------PKKEIMSTESLELLRKSG 269

Human   143 IQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELDFFEIL 207
            |.|:|||..||:...|::|||.||:::.:.|.|:::|:.||.|:||.||.|.::|..:.||...:
Yeast   270 INFEKHENLGIDVFEFSQLLMDSGLMMDDSVTWITYHAAYDLGFLINILMNDSMPNNKEDFEWWV 334

Human   208 RLFFPVIYDVKYLMKSCKNLKG---------------GLQEVAEQLELERIGPQHQAGSDSLLTG 257
            ..:.|..||:..:.|..:..|.               .|..:|::|.|.|.......|..|||..
Yeast   335 HQYMPNFYDLNLVYKIIQEFKNPQLQQSSQQQQQQQYSLTTLADELGLPRFSIFTTTGGQSLLML 399

Human   258 MAFFKMREMF---FEDHIDDAKYCGHLYGL 284
            ::|.::.::.   |.:..|.|||.|.:||:
Yeast   400 LSFCQLSKLSMHKFPNGTDFAKYQGVIYGI 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CNOT7	NP_001309022.1	CAF1	1..301	CDD:474062	104/290 (36%)
POP2	NP_014450.3	POP2	141..433	CDD:227553	104/290 (36%)