Protein Alignment ALG5 and Dpm1

DIOPT Version :10

• Sequence 1: NP_037470.1
• Gene: ALG5 / 29880
• HGNCID: 20266
• Length: 324
• Species: Homo sapiens
• Sequence 2: NP_609980.1
• Gene: Dpm1 / 35240
• FlyBaseID: FBgn0032799
• Length: 241
• Species: Drosophila melanogaster
• Alignment Length: 251
• Identity: 72/251 - (28%)
• Similarity: 122/251 - (48%)
• Gaps: 22/251 - (8%)

Human    63 PTK--QLSVVVPSYNEEKRLPVMMDEALSYLEKRQKRDPAFTYEVIVVDDGSKDQTSKVAFKYCQ 125
            ||.  :.|:::|:|||:..||:::...:.|:     :.....|||||:||||.|.|..|| |..|
  Fly     2 PTNGHKYSILMPTYNEKDNLPIIIWLIVKYM-----KASGLEYEVIVIDDGSPDGTLDVA-KDLQ 60

Human   126 K-YGSDKVRVITLVKNRGKGGAIRMGIFSSRGEKILMADADGA--TKF-PDVEKLEKGLNDLQPW 186
            | ||.||:.:.......|.|.|...||..:.|:.|::.|||.:  .|| |:..||::..|
  Fly    61 KIYGEDKIVLRPRGSKLGLGTAYIHGIKHATGDFIVIIDADLSHHPKFIPEFIKLQQEGN----- 120

Human   187 PNQMAIACGSRAHLEKESIAQRSYFRTLLMYGFHFLVWFLCVKGIRDTQCGFKLFTREAASRTFS 251
               ..|..|:| :.....:....:.|.|:..|.:||...|......|....|:|:.::...:..:
  Fly   121 ---YDIVSGTR-YAGNGGVFGWDFKRKLISRGANFLSQVLLRPNASDLTGSFRLYKKDVLEKCIA 181

Human   252 SLHVERWAFDVELLYIAQFFKIPIAEIAVNWTE-IEGSKLVPFWSWLQMGKDLLFI 306
            |...:.:.|.:|:|..|:.....|||:.:.:.: |.|:..:.....:|..|:||::
  Fly   182 SCVSKGYVFQMEMLVRARQHGYTIAEVPITFVDRIYGTSKLGGTEIIQFAKNLLYL 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ALG5	NP_037470.1	DPG_synthase	69..289	CDD:133031	65/224 (29%)
Dpm1	NP_609980.1	PLN02726	3..241	CDD:215385	71/250 (28%)