Protein Alignment GUCY1A1 and CG14877

DIOPT Version :9

• Sequence 1: NP_000847.2
• Gene: GUCY1A1 / 2982
• HGNCID: 4685
• Length: 690
• Species: Homo sapiens
• Sequence 2: NP_650507.1
• Gene: CG14877 / 41929
• FlyBaseID: FBgn0038380
• Length: 254
• Species: Drosophila melanogaster
• Alignment Length: 237
• Identity: 51/237 - (21%)
• Similarity: 81/237 - (34%)
• Gaps: 75/237 - (31%)

Human    38 ESCKATVPICQDIPEKNIQESLPQRKTSRSRVYLHTLAESICK-----------LIFPEFERLNV 91
            :.|.||   |::.|.::                    .|:||.           ::.|:......
  Fly    15 KDCVAT---CREEPARD--------------------CEAICDANGRNCTIRALVLLPDDNMYQA 56

Human    92 ALQRTLAKHKIKESR---KSL--EREDFEKTIAEQAVAAGVPVEVIKESLGEEVFKICYEEDENI 151
            :|.|.|...|:.|.:   |||  ...|||....:....|.  :.|||...|  :.|.|.:
  Fly    57 SLPRVLPILKVAEQQIRSKSLIPSHIDFEWLAHDTKCDAS--LGVIKAMDG--IIKQCAQ----- 112

Human   152 LGVVGGTLKDF-LNSFSTLLK----QSSHCQEAGKRGRLEDASILCLDKEDDFLHVYYFFPKRTT 211
              |:.|.:.|: |.:.|.:.|    |.:.....|  |...|......|..|:|     :...||.
  Fly   113 --VIFGPVCDYSLAAVSRITKYFNSQGTPLISVG--GSTYDFEQKKTDCNDEF-----YMLLRTG 168

Human   212 SLILPGIIKAAAHVL-----------YETEVEVSL--MPPCF 240
            .|....|.:...:|:           ||.:.:.|:  |..||
  Fly   169 MLSFETISELTINVMKRHNWSHSIFYYERDGQRSVAGMHTCF 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GUCY1A1	NP_000847.2	HNOBA	277..466	CDD:400168
		Guanylate_cyc	472..643	CDD:306677
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	43/183 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900