Protein Alignment Ndrg3 and MESK2

DIOPT Version :9

• Sequence 1: NP_001342320.1
• Gene: Ndrg3 / 29812
• MGIID: 1352499
• Length: 388
• Species: Mus musculus
• Sequence 2: NP_995914.1
• Gene: MESK2 / 37451
• FlyBaseID: FBgn0043070
• Length: 485
• Species: Drosophila melanogaster
• Alignment Length: 385
• Identity: 141/385 - (36%)
• Similarity: 205/385 - (53%)
• Gaps: 37/385 - (9%)

Mouse     1 MDELQDVQLTEIKPLLNDKNGTRNFQDFDCQEHDIETPHGMVHVTIRGLPKGNRPVILTYHDIGL 65
            :|.:.|::|..::  |...|...:..: .|::..:.|..|.|||.|:|  ...:|.|:||||:||
  Fly    20 VDPMDDIELRSVQ--LQFPNARGSILE-ACEQRRVPTDKGDVHVAIQG--DTAKPAIITYHDLGL 79

Mouse    66 NHKSCFNTFFNFEDMQEITQHFAVCHVDAPGQQEAAPSFPTGYQYPTMDELAEMLPPVLTHLSMK 130
            |:.:.|..||||..|:.:.::|.|.||.||||:|.||:.|..|.|||||:||..|..||:|..:|
  Fly    80 NYATSFAGFFNFPVMRGLLENFCVYHVTAPGQEEGAPTLPEDYVYPTMDDLAAQLLFVLSHFGLK 144

Mouse   131 SIIGIGVGAGAYILSRFALNHPELVEGLVLINIDPCAKGWIDWAAS-------KLSGFTTNIVDI 188
            |:||.||||||.||:|||..||:.|..|.|||......|||:|...       :..|.|..::|.
  Fly   145 SVIGFGVGAGANILARFAHAHPDKVGALCLINCVSTQSGWIEWGYQSFNARFLRTKGMTQGVIDY 209

Mouse   189 ILAHHFGQEELQANLDLIQTYRLHIAQDINQENLQLFLGSYNGRRDLEIER--PILGQNDNRLKT 251
            ::.||||:...:.|.||:|.|:.|..:.:|..||.:.:.:|..|.||.:.|  |....::....|
  Fly   210 LMWHHFGRNPEERNHDLVQMYKQHFERGVNPTNLAMLINAYIHRNDLHLARTPPGTPGSETAATT 274

Mouse   252 LKCSTLLVVGDNSPAVEAVVECNSRLDPINTTLLKMADCGGLPQVVQPGKLTEAFKYFLQGMGYI 316
            ||...:.:.|..||.|:..|..|.||||.|::.:|::|| .|....||.||.|||:.||||.||
  Fly   275 LKMPVINITGSLSPHVDDTVTFNGRLDPTNSSWMKISDC-ALVLEEQPAKLAEAFRLFLQGEGY- 337

Mouse   317 PYVQLSHLSSESVPSASMTRLARSRTHSTSSSIGSGESPFSRSVTSNQSDGTQESCESPD 376
                   .:..|.|:              ||..|:....:|....:|..:..|::.|..|
  Fly   338 -------ATPLSTPA--------------SSPCGTKYHTYSSIFFANFREQQQQAMEERD 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ndrg3	NP_001342320.1	Ndr	32..317	CDD:397285	125/293 (43%)
MESK2	NP_995914.1	Abhydrolase	51..337	CDD:304388	123/288 (43%)
		MhpC	57..334	CDD:223669	119/279 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850099
Domainoid	1	1.000	234	1.000	Domainoid score	I2376
eggNOG	1	0.900	-	-		E1_KOG2931
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40903
Inparanoid	1	1.050	241	1.000	Inparanoid score	I3317
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55737
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000626
OrthoInspector	1	1.000	-	-		otm42388
orthoMCL	1	0.900	-	-		OOG6_103361
Panther	1	1.100	-	-	O	PTHR11034
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5286
SonicParanoid	1	1.000	-	-		X370
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.830