DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mga and bi

DIOPT Version :9

Sequence 1:	XP_006499750.1	Gene:	Mga / 29808	MGIID:	1352483	Length:	3091	Species:	Mus musculus
Sequence 2:	NP_001259238.1	Gene:	bi / 31379	FlyBaseID:	FBgn0000179	Length:	1023	Species:	Drosophila melanogaster

Alignment Length:	255	Identity:	117/255 - (45%)
Similarity:	160/255 - (62%)	Gaps:	19/255 - (7%)

- Green bases have known domain annotations that are detailed below.

Mouse    69 DCTVGKITVTLDNNSMWNEFHNRSTEMILTKQGRRMFPYCRYWITGLDSNLKYILVMDISPVDSH 133
            |..|....|||:...:|.:||...|||::||.||:|||..::.::|||:..||||::||...|.:
  Fly   322 DGVVDDPKVTLEGKDLWEKFHKLGTEMVITKSGRQMFPQMKFRVSGLDAKAKYILLLDIVAADDY 386

Mouse   134 RYKWNGRWWEPSGKAEPHILGRVFIHPESPSTGHYWMHQPVSFYKLKLTNNTLDQEGHI---ILH 195
            |||::...|..:|||:|.:..|::|||:||:||..||.:.|||:|||||||..|:.|.:   ||:
  Fly   387 RYKFHNSRWMVAGKADPEMPKRMYIHPDSPTTGEQWMQKVVSFHKLKLTNNISDKHGFVSTTILN 451

Mouse   196 SMHRYLPRLHLVPAEKATEVIQLNGPGVHTFTFPQTEFFAVTAYQNIQITQLKIDYNPFAKGFRD 260
            |||:|.||.|||   :|.::::|......|:.|.:|||.|||||||.:|||||||.|||||||||
  Fly   452 SMHKYQPRFHLV---RANDILKLPYSTFRTYVFKETEFIAVTAYQNEKITQLKIDNNPFAKGFRD 513

Mouse   261 DGLSSKPQREGKQRNSSDQEGNSVSSSPAH----RVRLTEGEGSEIHSGDFDPVLRGHEA 316
            .|..   :||.||...|::..:|...:|.|    |..|..|     |:|. .|.|..|.|
  Fly   514 TGAG---KREKKQALMSNRGSDSDKLNPTHVSSSRAPLHLG-----HAGR-PPHLHPHAA 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mga	XP_006499750.1	TBOX	74..264	CDD:238106	98/192 (51%)
		DUF4801	1038..1080	CDD:374336
		DUF5585	<1510..>1811	CDD:375359
		Atrophin-1	1729..>2023	CDD:367360
		bHLHzip_MGA	2452..2516	CDD:381481
bi	NP_001259238.1	Optomotor-blind	<260..318	CDD:287988
bi	NP_001259238.1	T-box	330..513	CDD:279278	95/185 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810