DRSC/TRiP Functional Genomics Resources

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Protein Alignment REPIN1 and CG1647

DIOPT Version :9

Sequence 1:NP_001374966.1 Gene:REPIN1 / 29803 HGNCID:17922 Length:626 Species:Homo sapiens
Sequence 2:NP_651636.1 Gene:CG1647 / 43401 FlyBaseID:FBgn0039602 Length:1222 Species:Drosophila melanogaster


Alignment Length:351 Identity:71/351 - (20%)
Similarity:106/351 - (30%) Gaps:128/351 - (36%)


- Green bases have known domain annotations that are detailed below.


Human   297 CACCGKRFRH-------KP-NLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPC 353
            |....|:.|:       :| .||..:|:...|||.. ...|||          .|...||:.:| 
  Fly    89 CYATNKQTRNLLGLKQIEPARLIDLKRIVKEERPIS-GAVGKR----------GRKRKGEESWP- 141

Human   354 KECGRRFRHKPNLLSHSKI-HKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEPPPG 417
                :....||.:...|.: ||:.:                      .:|:....|...:||...
  Fly   142 ----KNNNVKPQVKKESFVWHKKQK----------------------LQPSQITSLVSKREPEIK 180

Human   418 APPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSR 482
            ..|......::.||                                     |..|:|:       
  Fly   181 DEPAEQDTSLKGPP-------------------------------------KKAGRKS------- 201

Human   483 VHSGERPFACEECGRRFSQGSHLAAHRRD--HAPDRP-FVCPDCGKAFRHKPYLAAHRRIHTGEK 544
                    .|..||.:| ....||...:.  |.|..| ::|..|.:...::..:.||:..|...|
  Fly   202 --------ICSVCGEKF-LSKELADEHKSLVHVPSIPRYICNACNQTHHNQSDIRAHQLWHKLSK 257

Human   545 -PYVCPDCGKAFSQKSNLVSHRRIHTGERPY-------ACPDCDRSFSQKSNLITHRKSHIRDGA 601
             ||.||.|..:.:.......|.|.||...|.       .||.|.::|.......|||        
  Fly   258 TPYKCPLCESSVANAYAFTRHLREHTPPTPVQLLVLDRECPLCKKTFVTNFFYNTHR-------- 314

Human   602 FCCAI-------CGQTFDDEERLLAH 620
              |||       |.:|.:.|...:.|
  Fly   315 --CAIRKRKCGGCSRTLNTEAAYMRH 338

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
REPIN1NP_001374966.1 C2H2 Zn finger 118..138 CDD:275368
C2H2 Zn finger 146..166 CDD:275368
C2H2 Zn finger 177..197 CDD:275368
COG5048 <197..371 CDD:227381 19/81 (23%)
C2H2 Zn finger 206..227 CDD:275368
C2H2 Zn finger 238..258 CDD:275368
COG5048 292..599 CDD:227381 64/321 (20%)
C2H2 Zn finger 297..317 CDD:275368 7/27 (26%)
C2H2 Zn finger 325..345 CDD:275368 4/19 (21%)
C2H2 Zn finger 353..373 CDD:275368 3/20 (15%)
C2H2 Zn finger 436..456 CDD:275368 0/19 (0%)
C2H2 Zn finger 464..484 CDD:275368 3/19 (16%)
C2H2 Zn finger 492..512 CDD:275368 6/21 (29%)
C2H2 Zn finger 520..540 CDD:275368 4/19 (21%)
C2H2 Zn finger 548..568 CDD:275368 5/19 (26%)
C2H2 Zn finger 576..596 CDD:275368 7/19 (37%)
C2H2 Zn finger 604..624 CDD:275368 7/24 (29%)
CG1647NP_651636.1 zf-AD 19..99 CDD:285071 3/9 (33%)
C2H2 Zn finger 203..224 CDD:275368 6/21 (29%)
C2H2 Zn finger 233..253 CDD:275368 4/19 (21%)
C2H2 Zn finger 262..282 CDD:275368 5/19 (26%)
C2H2 Zn finger 297..314 CDD:275368 5/16 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24406
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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