DRSC/TRiP Functional Genomics Resources

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Protein Alignment REPIN1 and CG8089

DIOPT Version :9

Sequence 1:NP_001374966.1 Gene:REPIN1 / 29803 HGNCID:17922 Length:626 Species:Homo sapiens
Sequence 2:NP_611014.1 Gene:CG8089 / 36679 FlyBaseID:FBgn0033993 Length:624 Species:Drosophila melanogaster


Alignment Length:582 Identity:124/582 - (21%)
Similarity:180/582 - (30%) Gaps:256/582 - (43%)


- Green bases have known domain annotations that are detailed below.


Human    94 SRGLRQQGTSVAQ-SGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAP 157
            |.|.|:   ||:| :|.:|.|...         |...||:|...||.      |.:|    .:.|
  Fly   136 SSGYRR---SVSQLAGQEAHGALR---------PKIAALFLPGLRCD------CYKC----ENLP 178

Human   158 FLAL-----HRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRR- 216
            :..|     |::.|..:.   .|.|.:|.:.|....:|..|:...|.:.|.:.    |.:.::| 
  Fly   179 WKKLQDVEDHQKTHRYSD---NFHCQICYRRFYLQHSLTSHIIRKSTSSRELH----ENKRYKRL 236

Human   217 ---------KQLRAHLRRCH----PPAPEARPFI------------------CGNC----GRSFA 246
                     |:|...|.:..    |.|.:.:.:.                  |.:|    |.||:
  Fly   237 LENQKSQEEKELELSLNKVEDILVPVAEDLQSYFKDESKHPIQKRKTSSLSKCPSCAQNYGFSFS 301

Human   247 QWDQLVAHKRVHVAEALEEAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLI 311
            ....:|.|:|..:                              ..:.||.|:.|.:.|..:..|.
  Fly   302 HQLHMVKHRRERL------------------------------YTNFPFHCSFCNRSFLTRKFLR 336

Human   312 AH-RRVHTGE----RPHQCPECGKRFTNKPYLTSH-RRIHTGEKP---------------YPCKE 355
            .| :||.|..    ||.:||.|..||..|..|.|| .|||...||               :..||
  Fly   337 KHQQRVRTFSTLLYRPFKCPHCTWRFQLKSALDSHVLRIHERRKPCLICKLPTSRLCCSAHTSKE 401

Human   356 CGR---RFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEPPPG 417
            |.|   ::|.|                                            ::|.:|||.|
  Fly   402 CNRAMQKYRDK--------------------------------------------MRPLREPPKG 422

Human   418 APPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAH-QRQHTGERPFTCAECGKNFGKKTHLVAHS 481
            ...:.| .|:        |..|.|.|..:.||..| .:.|..:|.|||..||.||          
  Fly   423 GCRKQP-TPV--------CKICNRKFTRKFFLEEHMNKAHLNKRNFTCEICGANF---------- 468

Human   482 RVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPY 546
                             :|||: :..||:                       |.|..:||.:   
  Fly   469 -----------------YSQGT-MQTHRK-----------------------AVHLLVHTVQ--- 489

Human   547 VCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRK-------SHIRDGA 601
             |..|......|.|...|              | :|.|.|.||:...|       |:.|.||
  Fly   490 -CEVCDLTIKSKGNYRRH--------------C-KSQSHKDNLVKFGKNNDKTKDSNRRKGA 535

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
REPIN1NP_001374966.1 C2H2 Zn finger 118..138 CDD:275368 4/19 (21%)
C2H2 Zn finger 146..166 CDD:275368 5/24 (21%)
C2H2 Zn finger 177..197 CDD:275368 5/19 (26%)
COG5048 <197..371 CDD:227381 49/233 (21%)
C2H2 Zn finger 206..227 CDD:275368 5/30 (17%)
C2H2 Zn finger 238..258 CDD:275368 8/23 (35%)
COG5048 292..599 CDD:227381 77/338 (23%)
C2H2 Zn finger 297..317 CDD:275368 6/20 (30%)
C2H2 Zn finger 325..345 CDD:275368 10/20 (50%)
C2H2 Zn finger 353..373 CDD:275368 6/22 (27%)
C2H2 Zn finger 436..456 CDD:275368 7/20 (35%)
C2H2 Zn finger 464..484 CDD:275368 5/19 (26%)
C2H2 Zn finger 492..512 CDD:275368 5/19 (26%)
C2H2 Zn finger 520..540 CDD:275368 2/19 (11%)
C2H2 Zn finger 548..568 CDD:275368 5/19 (26%)
C2H2 Zn finger 576..596 CDD:275368 7/26 (27%)
C2H2 Zn finger 604..624 CDD:275368
CG8089NP_611014.1 C2H2 Zn finger 289..309 CDD:275368 6/19 (32%)
C2H2 Zn finger 322..343 CDD:275368 6/20 (30%)
C2H2 Zn finger 355..376 CDD:275368 10/20 (50%)
C2H2 Zn finger 432..453 CDD:275368 7/20 (35%)
C2H2 Zn finger 461..486 CDD:275368 12/75 (16%)
C2H2 Zn finger 490..506 CDD:275368 4/15 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24406
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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