DRSC/TRiP Functional Genomics Resources

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Protein Alignment REPIN1 and CG10431

DIOPT Version :9

Sequence 1:NP_001374966.1 Gene:REPIN1 / 29803 HGNCID:17922 Length:626 Species:Homo sapiens
Sequence 2:NP_001286078.1 Gene:CG10431 / 35157 FlyBaseID:FBgn0032730 Length:762 Species:Drosophila melanogaster


Alignment Length:563 Identity:111/563 - (19%)
Similarity:176/563 - (31%) Gaps:187/563 - (33%)


- Green bases have known domain annotations that are detailed below.


Human    24 VGRSRRCSRG------------SIPRNIPKRSWK-KPH-------------PQLCSLQEEEPMLE 62
            ||:|.|...|            :...|..|..|: .||             |.......:.|.|:
  Fly   281 VGQSERLQPGRTANEMLQNELLTEEHNYAKEEWQLPPHQYKTEKVEGTDAAPDAAPPPADPPPLQ 345

Human    63 -----------RRCRGPLAMGLAQ---PRLLSGPSQESPQTLGKESRGLRQQGTSVAQSGAQAPG 113
                       |.|: |:...::|   |.:.....|.:|.|..|.:  :.....||.:|.|..  
  Fly   346 DNIDPPSAPEPRSCK-PIVTNVSQIPNPMICELLPQPAPPTSIKPN--IVVLNDSVVESSAAF-- 405

Human   114 RAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAATPDLGF-AC 177
            |.|.|..|...|                  :......:.:.|:         |:.:||.:.. ..
  Fly   406 RLHNCTLCTAKF------------------ITIDSLNQHYAHS---------HSNSTPMVSVPPM 443

Human   178 HLC-----------GQSFRGWVAL----VLHLRAHSA--AKRP---IACPKCERRFWRRKQLRAH 222
            ::|           .:|.||.||.    ...|..|::  :|:|   |.....:..|...|.|...
  Fly   444 NICLPSLTMNPPMKMESNRGLVATEQSEYWPLEWHNSPVSKQPRKKIDILDMQSSFLHHKDLIPT 508

Human   223 LRRCHPPAPEARPFICGNCGRSFAQWDQLVA-----HKRVHVAEALEEAAAKALGPRPRGRPAVT 282
            ..:...|||:                .||||     .|..:....|:....|...||...|    
  Fly   509 ATQLSAPAPD----------------PQLVAVTASYAKLANRYRKLQLKCKKLKSPRKVHR---- 553

Human   283 APRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPH----------QCPECGKRFTNKPY 337
                      :.:.|..|.|.|....||..|||    ::.|          :|..|.|.|.::..
  Fly   554 ----------KTYVCRMCRKGFSKFKNLHHHRR----QKAHFVKLIPNFSGRCSGCLKFFRSRLG 604

Human   338 LTSHRRI---------HTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPA 393
            |..|.|.         |...:.:.|:.|      :....:|.::::|.|             |..
  Fly   605 LRQHMRYICQSLSLKNHRRLQSFKCRHC------QAIAFAHWRLYRRHE-------------LNC 650

Human   394 GPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTG 458
            .|::|..:...|:..|..                ..|..::.|:.|.:||.....||.|...|:.
  Fly   651 RPKKSKTKVQTAMNSKKK----------------VTPTQVFECNICKKSFGSLNGLRQHNITHST 699

Human   459 ERPFTCAECGKNFGKKTHLVAHSR-VHSGERPFACEECGRRFS 500
            ||...|..|.:.|.::..|..|.: .|...:|..|..|..|::
  Fly   700 ERQHKCGICERVFKRRNGLSQHIKGYHLQLKPHECPVCQHRYA 742

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
REPIN1NP_001374966.1 C2H2 Zn finger 118..138 CDD:275368 3/19 (16%)
C2H2 Zn finger 146..166 CDD:275368 1/19 (5%)
C2H2 Zn finger 177..197 CDD:275368 7/34 (21%)
COG5048 <197..371 CDD:227381 41/202 (20%)
C2H2 Zn finger 206..227 CDD:275368 3/20 (15%)
C2H2 Zn finger 238..258 CDD:275368 5/24 (21%)
COG5048 292..599 CDD:227381 49/229 (21%)
C2H2 Zn finger 297..317 CDD:275368 9/19 (47%)
C2H2 Zn finger 325..345 CDD:275368 7/28 (25%)
C2H2 Zn finger 353..373 CDD:275368 3/19 (16%)
C2H2 Zn finger 436..456 CDD:275368 7/19 (37%)
C2H2 Zn finger 464..484 CDD:275368 5/20 (25%)
C2H2 Zn finger 492..512 CDD:275368 3/9 (33%)
C2H2 Zn finger 520..540 CDD:275368
C2H2 Zn finger 548..568 CDD:275368
C2H2 Zn finger 576..596 CDD:275368
C2H2 Zn finger 604..624 CDD:275368
CG10431NP_001286078.1 THAP 4..81 CDD:283206
zf-AD 123..192 CDD:214871
zf-C2H2_6 674..700 CDD:290623 8/25 (32%)
C2H2 Zn finger 677..697 CDD:275368 7/19 (37%)
C2H2 Zn finger 705..726 CDD:275368 5/20 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24406
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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