Protein Alignment ZDHHC1 and Dnz1

DIOPT Version :10

• Sequence 1: NP_037436.1
• Gene: ZDHHC1 / 29800
• HGNCID: 17916
• Length: 485
• Species: Homo sapiens
• Sequence 2: NP_477449.1
• Gene: Dnz1 / 34503
• FlyBaseID: FBgn0027453
• Length: 276
• Species: Drosophila melanogaster
• Alignment Length: 267
• Identity: 74/267 - (27%)
• Similarity: 109/267 - (40%)
• Gaps: 64/267 - (23%)

Human    53 IVAWL--------LYLFFAVIGFGILVPLLPHHWVPAGYACMGAIFAGHLVVHLTAVSIDPADAN 109
            ::.|:        |::.|.|:.|..:|.||       ..:...|:|:....|.|.|..:|.:|.:
  Fly    27 VIRWIILTTMPGSLWMSFHVVLFNTVVFLL-------AMSHSKAVFSDPGTVPLPANRLDFSDLH 84

Human   110 VRDKSYAGPLPIFNRSQHAHVIEDLHCNLCNVDVSARSKHCSACNKCVCGFDHHCKWLNNCVGER 174
            ..:|:...|       .:.|..|...|..|......|:.||..|.:|:...||||.|:|||||||
  Fly    85 TTNKNNPPP-------GNGHSSEWTVCTRCETYRPPRAHHCRICKRCIRRMDHHCPWINNCVGER 142

Human   175 NYRLFLHSVASALLGVLLLVLVATYVFVEFFVNPMRLRTNRHFEVLKNHTDVWFVFLPAAPVETQ 239
            |.:.||    ..|:.|.||.|.:..:.|..:|.|..       |..:|            .:|||
  Fly   143 NQKYFL----QFLIYVALLSLYSIALIVGSWVWPCE-------ECSQN------------VIETQ 184

Human   240 APAILALAALLI--LLGLLSTALLGHLLCFHIYLMWHKLTTYEYIVQHRPPQEAKGVHRELESCP 302
            ...|.::..:|:  |.||..||::...|  |..|  :..|..|.|.|       ||.:|
  Fly   185 LRMIHSVILMLVSALFGLFVTAIMVDQL--HAIL--YDETAVEAIQQ-------KGTYR------ 232

Human   303 PKMRPIQ 309
            |..|..|
  Fly   233 PNRRKYQ 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZDHHC1	NP_037436.1	Mediates interaction with STING1. /evidence=ECO:0000269|PubMed:25299331	1..271		63/227 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41
		DHHC	129..284	CDD:396215	50/156 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	324..358
		DPBB_RlpA_EXP_N-like	<362..>400	CDD:455124
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	462..485
Dnz1	NP_477449.1	DHHC	97..228	CDD:396215	51/164 (31%)