Protein Alignment TMOD2 and tmod

DIOPT Version :10

• Sequence 1: NP_055363.1
• Gene: TMOD2 / 29767
• HGNCID: 11872
• Length: 351
• Species: Homo sapiens
• Sequence 2: NP_001247372.1
• Gene: tmod / 43633
• FlyBaseID: FBgn0082582
• Length: 567
• Species: Drosophila melanogaster
• Alignment Length: 347
• Identity: 122/347 - (35%)
• Similarity: 196/347 - (56%)
• Gaps: 17/347 - (4%)

Human     5 FQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHL 69
            :.|:|.:|.::|.:.||.:||.||:..|..   ::||:...||...|...:..|.||||.:|:.|
  Fly    91 YGKDLSEYDDVDVESLLAQLSPEEITILAK---EVDPDDNFLPPDQRNSYECTKEATGPLNRKQL 152

Human    70 LMYLEKEALEQKDREDFVPFT-GEKKGRVFIPKEKPI-ETRKEEKVTLD--PELEEALASASDTE 130
            :.::.|:|:|..|:.:|.||. |:.:|:.::|..:.. :...||::.:|  .|.|.||..|:..|
  Fly   153 IEHINKQAIETPDQPEFEPFVQGKVRGKKWVPPPRDARDIEAEEQIAIDMGEEYEHALNDATQEE 217

Human   131 LYDLAAVLGVHNLLNNPKFDEETANNKGGKG-PV----RNVVKGEKVKPVFEEPPNPTNVEISLQ 190
            :.||||:||.|:::|..::.....|    || ||    ..:.|..:.|....:|||.|:||.|::
  Fly   218 IIDLAAILGFHSMMNQDQYHASLLN----KGQPVGLGWDGITKSTQQKLFPMDPPNNTDVEESIK 278

Human   191 QMKANDPSLQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSNDPVAIAFADMLKVNKT 255
            ::|.:|..|.::||||||||....|.:...||..|.|::..||......|..|:..|..::.:||
  Fly   279 RVKDDDSKLIDLNLNNIKNISDEKLEQLFAALPQNEHLEVLSLTNVGLTDKTALLLAAAIEKSKT 343

Human   256 LTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQ-LGTAVEMEIAQMLEENSRILKFGY 319
            |..||:|:|||:...|:.||:||.:..|:.|.:..|||.. ||..:||||..::|:||.:|:.|.
  Fly   344 LRVLNVETNFISPPVIVKLVQALLKCHTIEEFRASNQRSAVLGNKIEMEITDLVEKNSSLLRLGL 408

Human   320 QFTKQGPRTRVAAAITKNNDLV 341
            .......|.||||.:.:|.|.:
  Fly   409 HLEFNDARHRVAAHLQRNIDRI 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMOD2	NP_055363.1	Tropomodulin	5..146	CDD:460862	49/144 (34%)
		RNA1	<209..338	CDD:444072	47/129 (36%)
tmod	NP_001247372.1	Tropomodulin	91..233	CDD:460862	49/144 (34%)
		PPP1R42	<285..421	CDD:455733	52/135 (39%)