DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Galnt7 and Pgant9

DIOPT Version :9

Sequence 1:	NP_075215.1	Gene:	Galnt7 / 29750	RGDID:	620362	Length:	657	Species:	Rattus norvegicus
Sequence 2:	NP_001097342.1	Gene:	Pgant9 / 246627	FlyBaseID:	FBgn0050463	Length:	650	Species:	Drosophila melanogaster

Alignment Length:	655	Identity:	235/655 - (35%)
Similarity:	331/655 - (50%)	Gaps:	103/655 - (15%)

- Green bases have known domain annotations that are detailed below.

  Rat    34 DPSPLSRMR----EDRDVNNPLPNRGGNGLAPGDDRFKPVVPWPHVEGVEVDLESIRRKNKAKNE 94
            ||..|:...    ||..:|..:...||...|..:....|.| ..|    :.||::.|.:.||..:
  Fly    64 DPIALALRNEPAGEDFGINGNVIGGGGQKQAHDEADIPPTV-GKH----KADLQAERMRKKAAEQ 123

  Rat    95 QERHAGGDSQKDIMQRQYLTFKPQTFTYRDPVLRPGVLGNFEPKEPEPHGVVGGPGENAKPLVL- 158
            .::....||:|.|                ||.      .|||.          .|||..||:.|
  Fly   124 PKKKPQEDSKKVI----------------DPP------ANFEE----------NPGELGKPVRLP 156

  Rat   159 ---GPEYKQAAQASIKEFGFNMAASDMISLDRSVNDLRQEECKYWHYDE-----NLLTSSVVIVF 215
               ..|.|:|......:..||...||:||:.|::.|.|...||    ||     ||..:.|:|.|
  Fly   157 KEMSDEMKKAVDDGWTKNAFNQYVSDLISVHRTLPDPRDAWCK----DEARYLTNLPKTDVIICF 217

  Rat   216 HNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKLTEYIKLWNGLVKVFRNERREGL 280
            |||.|:.|:||||||:.|:|...:.:|:|:||:|:..|||.:|.:|...: ..|::.|.::||||
  Fly   218 HNEAWTVLLRTVHSVLDRSPEHLIGKIILVDDYSDMPHLKRQLEDYFAAY-PKVQIIRGQKREGL 281

  Rat   281 IQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAPLVAPISKDRTICTVPIIDVINGNTYEIIPQGG 345
            |:||.:||..|| ..||.|||:|||....|..||:..|:::.|....|:||||:..|.|...:
  Fly   282 IRARILGANHAK-SPVLTYLDSHCECTEGWLEPLLDRIARNSTTVVCPVIDVISDETLEYHYR-- 343

  Rat   346 GDEDGYARGAWDWSMLWKRVPLTPREKRLRKTKTEPYRSPAMAGGLFAIERDFFFELGLYDPGLQ 410
             |..|...|.:||::.:...|:..||::...:..||..||.||||||:|:|:||..||.||.|..
  Fly   344 -DSGGVNVGGFDWNLQFSWHPVPERERKRHNSTAEPVYSPTMAGGLFSIDREFFDRLGTYDSGFD 407

  Rat   411 IWGGENFEISYKIWQCGGKLLFVPCSRVGHIYRLEG---WQGNPPPLYVGSSPTLKNYVRVVEVW 472
            ||||||.|:|:|.|.|||.|..||||.||||:|...   |:.       |.:...||.||:.|||
  Fly   408 IWGGENLELSFKTWMCGGTLEIVPCSHVGHIFRKRSPYKWRS-------GVNVLKKNSVRLAEVW 465

  Rat   473 WDEYKDYFYASRPESKALPYGDISELKKFREDHNCKSFKWFMEEIAYDITAHYP---LPPRNVEW 534
            .|||..|:|......|. .:||:|:.:|.|.|..||||||:::.|       ||   :|..:|..
  Fly   466 MDEYSQYYYHRIGNDKG-DWGDVSDRRKLRNDLKCKSFKWYLDNI-------YPELFIPGDSVAH 522

  Rat   535 GEIRGLETAY----CIDS-MGKTN-----GGFVELGPCHRMGGNQLFRINEANQLMQYDQCLTKG 589
            ||||.|  .|    |:|: .||.:     |.:    ||||.||||.:.:::|.::.:.|.||...
  Fly   523 GEIRNL--GYGGRTCLDAPAGKKHQKKAVGTY----PCHRQGGNQYWMLSKAGEIRRDDSCLDYA 581

  Rat   590 PDGSKVMITHCN---LNEFKEWQYFKNLHRFTHIASGKCLDRSEVLHQVFISSCDNGKMTQKWEM 651
              |..|.:..|:   .|:|  |.|.:|..:..|..|||||..||...::.:..|......|:|.:
  Fly   582 --GKDVTLFGCHGGKGNQF--WTYRENTKQLHHGTSGKCLAISESKDKLLMEECSASLSRQQWTL 642

  Rat   652 NNIHS 656
            .|..|
  Fly   643 ENYDS 647

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galnt7	NP_075215.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	30..66		9/35 (26%)
		Catalytic subdomain A	206..317		51/110 (46%)
		pp-GalNAc-T	210..518	CDD:133004	136/310 (44%)
		WcaA	210..>331	CDD:223539	53/120 (44%)
		Catalytic subdomain B	381..443		40/61 (66%)
		Ricin_B_lectin	534..649	CDD:279046	41/127 (32%)
		RICIN	535..651	CDD:238092	42/128 (33%)
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	125/282 (44%)
		pp-GalNAc-T	213..510	CDD:133004	137/316 (43%)
		Ricin_B_lectin	521..640	CDD:279046	41/128 (32%)
		RICIN	523..642	CDD:238092	42/128 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345966
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750