Protein Alignment Gabra6 and Rdl

DIOPT Version :9

• Sequence 1: NP_068613.1
• Gene: Gabra6 / 29708
• RGDID: 61861
• Length: 453
• Species: Rattus norvegicus
• Sequence 2: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Alignment Length: 551
• Identity: 172/551 - (31%)
• Similarity: 241/551 - (43%)
• Gaps: 156/551 - (28%)

  Rat    31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKF- 94
            |:|.|||:....||.|:||.:||...||...:||.|...:|:|:|::|:|.:|||.|||.||.:
  Fly    58 NISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYR 122

  Rat    95 KGP-AEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRLMHNGTILYTMRLTINADCPM 158
            |.| .|.||:.:..:..||.|||||.|.|:|..|..||.|:..|:.|:|:|..::||||.|.|||
  Fly   123 KRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPM 187

  Rat   159 RLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSN 223
            .|..||||...|.::..|:.|...:|.|.|:.| |.||.:..| ..|.|:.::|....:..|...
  Fly   188 NLQYFPMDRQLCHIEIESFGYTMRDIRYFWRDG-LSSVGMSSE-VELPQFRVLGHRQRATEINLT 250

  Rat   224 TGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSI 288
            ||.|..:.......|.|||::||||.|..:.||:|.||||:|:.:.|||...|:|||||||||..
  Fly   251 TGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMS 315

  Rat   289 SARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFT-NLQSQKA----------------- 335
            |...:|||:||..::|.::..||..||::|:|:|.|.|.. .:|.:|.
  Fly   316 STNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLD 380

  Rat   336 ---ERQA---------------------------------------------------------- 339
               ::||
  Fly   381 GANQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPK 445

  Rat   340 QTAAKPPVAKSKTTESL-------------EAEIVVHSDSKYHLKKRISSLTL------------ 379
            ||.:..|:..|...:::             |....|| |.|.|.|......|:
  Fly   446 QTVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVH-DPKAHSKGGTLENTVNGGRGGPQSHGP 509

  Rat   380 -----------------------------PIVPS-----SEASKVLSRTPILPSTPVTPPLLLPA 410
                                         ..||:     .:..||.....:|..||
  Fly   510 GPGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITP--------- 565

  Rat   411 IGGTSKIDQYSRILFPVAFAGFNLVYWIVYL 441
                |.||:||||:|||.|..|||:|||:||
  Fly   566 ----SDIDKYSRIVFPVCFVCFNLMYWIIYL 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gabra6	NP_068613.1	Neur_chan_LBD	33..240	CDD:280998	84/208 (40%)
		LIC	34..440	CDD:273305	168/545 (31%)
		Neur_chan_memb	247..437	CDD:280999	77/327 (24%)
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	72/184 (39%)
		Neur_chan_memb	274..588	CDD:397193	77/327 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910