Protein Alignment Gabrd and GluClalpha

DIOPT Version :10

• Sequence 1: NP_058985.1
• Gene: Gabrd / 29689
• RGDID: 61901
• Length: 449
• Species: Rattus norvegicus
• Sequence 2: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Alignment Length: 469
• Identity: 150/469 - (31%)
• Similarity: 236/469 - (50%)
• Gaps: 48/469 - (10%)

  Rat     6 WLLLPLLLLCTQPHHGARAMNDIGDYVGSNLEISWLPN----LDGLMEG--YARNFRP-GIGGP- 62
            |.:|....||:..             :.:|.:|::...    ||.::..  |....|| ||.|.
  Fly     8 WAILYFASLCSAS-------------LANNAKINFREKEKKVLDQILGAGKYDARIRPSGINGTD 59

  Rat    63 -PVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYNHTNETLG-LDSRFVDKLWLPDTF 125
             |..|.:.:.|.||..|.:..|||::.:...:.|.|.||.::.....|. |.....:::|:||.|
  Fly    60 GPAVVRVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKYLTLTEANRVWMPDLF 124

  Rat   126 IVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLAKYPMDEQECMLDLESYGYSSE 190
            ..|.|...||::.:.|..||:.|:|.:||||||:.|:||.|:|..||:|.|.|.|.:.|||:::.
  Fly   125 FSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTN 189

  Rat   191 DIVYYWSENQEQIHGLDRLQLAQFTITSYRFTTELMNFK-SAGQFPRLSLHFQLRRNRGVYIIQS 254
            |:|:.|.|. :.:..:..|.|.:||:.  :|.|:..|.| :.|::..|.:....:|....|:||.
  Fly   190 DLVFLWKEG-DPVQVVKNLHLPRFTLE--KFLTDYCNSKTNTGEYSCLKVDLLFKREFSYYLIQI 251

  Rat   255 YMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLMVSARSSLPRASAIKALDVYFWICYV 319
            |:|..:||.:||||||:.|.|||||||||:||:|||.|......:|||..|..||:||:..:|..
  Fly   252 YIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLT 316

  Rat   320 FVFAALVEYAFAHF------------NADYRKKRK----AKVKVTKPRAEMDVRNAIVLFSLSAA 368
            |||.||:|:|..::            ..:.:|||:    |.:.......:.|......:.|..|.
  Fly   317 FVFGALLEFALVNYASRSGSNKANMHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMASQFAR 381

  Rat   369 GVSQELAISRRQGRVPGNLMGSYRSVEVEAKKEGGSRPGGPGGIRSRLKPIDADTIDIYARAVFP 433
            |..|:..:.|.    ||:.:...:.::.|...:...||.......|:. |..:..||:.:|..||
  Fly   382 GGGQQKPLVRH----PGDPLALEKRLQCEVHMQAPKRPNCCKTWLSKF-PTRSKRIDVISRITFP 441

  Rat   434 AAFAAVNIIYWAAY 447
            ..||..|::||:.|
  Fly   442 LVFALFNLVYWSTY 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gabrd	NP_058985.1	LGIC_ECD	63..246	CDD:475126	62/184 (34%)
		LGIC_TM	249..>337	CDD:476813	45/99 (45%)
		TM1 helix	252..272	CDD:349850	12/19 (63%)
		TM2 helix	281..302	CDD:349850	10/20 (50%)
		TM3 helix	312..334	CDD:349850	9/33 (27%)
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	149/467 (32%)