Protein Alignment Cyp11a1 and Cyp12d1-d

DIOPT Version :10

• Sequence 1: NP_058982.1
• Gene: Cyp11a1 / 29680
• RGDID: 69325
• Length: 526
• Species: Rattus norvegicus
• Sequence 2: NP_995812.1
• Gene: Cyp12d1-d / 2768720
• FlyBaseID: FBgn0053503
• Length: 521
• Species: Drosophila melanogaster
• Alignment Length: 562
• Identity: 135/562 - (24%)
• Similarity: 239/562 - (42%)
• Gaps: 115/562 - (20%)

  Rat     9 RSVLVKSCQPFLSPV--WQGPGLATGNGAGISSTNSPRSFNEIPSPGDNGWINLYHFLR------ 65
            |||.:     ::.||  .:...:.....|..|.|...::::|||.|      |.:.|:|
  Fly     8 RSVAI-----YVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRP------NKFKFMRAFMPGG 61

  Rat    66 --ENGTHRIHYHHMQNFQKYGPIY--REKLGNMESVYILDPKDAATLFSCEGPNPERYLVPPWVA 126
              :|.:...:...|:  ::||.||  ....|..:.|...:.||...:|..||..|.|..:.. :.
  Fly    62 EFQNASITEYTSAMR--KRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDS-IV 123

  Rat   127 YHQYYQRP------IGVLFKSSDAWRKDRIVLNQEVMAPDSIKNFVPLLEGVAQDFIKVLHRRIK 185
            |.:.:.||      .|::...::||.|.|..:|...|.|..::.:...|..:..:||:.: :.|:
  Fly   124 YFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERI-KEIR 187

  Rat   186 QQNSGKFSGDISDDLFRFAFESITSVVFGERLGMLEEIVDPESQRFIDAVYQMFHTSVPM----- 245
            ...:.:...|.:|::.|..|||:..|.|..::|::.:..|..     ||: .:|.||..:
  Fly   188 DPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNS-----DAL-TLFQTSRDIFRLTF 246

  Rat   246 -LNMPPDLFRLFRTKTWKDHAAAWDVIFSKADEYTQNFYWDLRQKRDFSKYPGVLYSLL------ 303
             |::.|.::::..|.|::                        :.||..:....|...:|
  Fly   247 KLDIQPSMWKIISTPTYR------------------------KMKRTLNDSLNVSQKMLKENQDA 287

  Rat   304 ------GGNKLPFKNIQANITE------------MLAGGVDTTSMTLQWNLYEMAHNLKVQEMLR 350
                  .|.|:...::...:.|            :|..|||.|:..|...|..::.:...|..||
  Fly   288 LEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLR 352

  Rat   351 AEVLA--------ARRQAQGDMAKMVQLVPLLKASIKETLRLHPISVTLQRYIVNDLVLRNYKIP 407
            .|:|:        ...:...||       |.|:|.||||||.:|......|...||::|..|::|
  Fly   353 EELLSIMPTKDSLLNEENMKDM-------PYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVP 410

  Rat   408 AKTLVQVASYAMGRESSFFPNPNKFDPTRWLE-----KSQNTTHFRYLGFGWGVRQCLGRRIAEL 467
            ..|.|.:.|..:.:|::::|.|::|.|.|||.     |....:.|.:|.||:|.|.|:|:|:.:|
  Fly   411 KGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDL 475

  Rat   468 EMTIFLINVLENFRIEVQSIRDVGTKFNLILMPEKPIFFNFQ 509
            ||...:..::.||.:|..  ||....|..:.:.|..|.|.|:
  Fly   476 EMETTVAKLIRNFHVEFN--RDASRPFKTMFLMEPAITFPFK 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp11a1	NP_058982.1	cytochrome_P450	80..505	CDD:477761	115/475 (24%)
Cyp12d1-d	NP_995812.1	CYP24A1-like	76..515	CDD:410677	117/481 (24%)