Protein Alignment GTF2H3 and Tfb4

DIOPT Version :10

• Sequence 1: NP_001507.2
• Gene: GTF2H3 / 2967
• HGNCID: 4657
• Length: 308
• Species: Homo sapiens
• Sequence 2: NP_608574.2
• Gene: Tfb4 / 33294
• FlyBaseID: FBgn0031309
• Length: 299
• Species: Drosophila melanogaster
• Alignment Length: 332
• Identity: 62/332 - (18%)
• Similarity: 108/332 - (32%)
• Gaps: 112/332 - (33%)

Human    26 KSSAQAVRNVAELPLRWWGAGEKT-CEVSEGCQDLIMLLY-----NGPK-VNLVIIKGCTE---- 79
            |..|.|::.:.|       |.||. ||:|...|..|.|.|     :||| :||.:.:...|
  Fly   255 KKDAMAMQRLKE-------AAEKAKCELSSSVQTDINLPYLTMDASGPKHLNLKLTRAKLETLVG 312

Human    80 -------------VEDQE------------------PKV------IWLRTGPGLSV-----VSYT 102
                         :.|.|                  |||      ::.|. |..:|     |:..
  Fly   313 DLIKRTIAPCQKAMSDAEVSKSDIGEVLLVGGMTRMPKVQSLVQEVFGRQ-PSRAVNPDEAVAVG 376

Human   103 RVCRHGDLCNDVNSTKILEELPTPTGASVPGSLRCPLCLSNDSCENAPEQVCPVGSTHCYDGVLR 167
            ...:.|.|..||....:|:..|...|....|.:...|...|.:......||....:
  Fly   377 AAVQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTRLINRNTTIPTKKSQVFSTAA--------- 432

Human   168 LRGDGIRTNLKVQGCMAQPDCNLLNGTQAIGTLYMSENCDLIGPQALDCNSGSLETVRNVSD--- 229
               || :|.::::  :.|.:..:.:..:.:|:.      .|:|..........:|.|.::..
  Fly   433 ---DG-QTQVEIK--VHQGEREMASDNKMLGSF------TLVGIPPAPRGVPQIEVVFDIDANGI 485

Human   230 LHLSWTTGWQTCEAGEGCYETVM--------------LIQNGHEFHMVLTKGCTRDMNKKARLTR 280
            :|:|      ..:.|.|..:.::              :|:|..::       ...|..||.|:..
  Fly   486 VHVS------ARDKGTGKEQQIVIQSSGGLSKDEIENMIKNAEQY-------AQADKQKKDRIEA 537

Human   281 HRTGPGI 287
            .....||
  Fly   538 VNQAEGI 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GTF2H3	NP_001507.2	tfb4	7..289	CDD:273181	62/332 (19%)
Tfb4	NP_608574.2	Tfb4	15..276	CDD:461076	9/27 (33%)